Inspired by the classic problem of Boolean function monotonicity testing, we investigate the testability of other well-studied properties of combinatorial finite set systems, specifically intersecting families and union-closed families. A function f: {0,1}ⁿ → {0,1} is intersecting (respectively, union-closed) if its set of satisfying assignments corresponds to an intersecting family (respectively, a union-closed family) of subsets of [n].

Our main results are that - in sharp contrast with the property of being a monotone set system - the property of being an intersecting set system, and the property of being a union-closed set system, both turn out to be information-theoretically difficult to test. We show that:

- For ε ≥ Ω(1/√n), any non-adaptive two-sided ε-tester for intersectingness must make 2^{Ω(n^{1/4}/√{ε})} queries. We also give a 2^{Ω(√{n log(1/ε)})}-query lower bound for non-adaptive one-sided ε-testers for intersectingness.

- For ε ≥ 1/2^{Ω(n^{0.49})}, any non-adaptive two-sided ε-tester for union-closedness must make n^{Ω(log(1/ε))} queries.

Thus, neither intersectingness nor union-closedness shares the poly(n,1/ε)-query non-adaptive testability that is enjoyed by monotonicity.

To complement our lower bounds, we also give a simple poly(n^{√{nlog(1/ε)}},1/ε)-query, one-sided, non-adaptive algorithm for ε-testing each of these properties (intersectingness and union-closedness). We thus achieve nearly tight upper and lower bounds for two-sided testing of intersectingness when ε = Θ(1/√n), and for one-sided testing of intersectingness when ε = Θ(1).