2026-07-23T00:18:42Z https://drops.dagstuhl.de/oai

oai:drops-oai.dagstuhl.de:12962 2024-03-06T10:51:11Z ddc:004 open_access

scadnano: A Browser-Based, Scriptable Tool for Designing DNA Nanostructures Doty, David Lee, Benjamin L Stérin, Tristan computer-aided design structural DNA nanotechnology DNA origami We introduce scadnano (short for "scriptable cadnano"), a computational tool for designing synthetic DNA structures. Its design is based heavily on cadnano [Douglas et al., 2009], the most widely-used software for designing DNA origami [Paul W. K. Rothemund, 2006], with three main differences: 1) scadnano runs entirely in the browser, with no software installation required. 2) scadnano designs, while they can be edited manually, can also be created and edited by a well-documented Python scripting library, to help automate tedious tasks. 3) The scadnano file format is easily human-readable. This goal is closely aligned with the scripting library, intended to be helpful when debugging scripts or interfacing with other software. The format is also somewhat more expressive than that of cadnano, able to describe a broader range of DNA structures than just DNA origami. Schloss Dagstuhl – Leibniz-Zentrum für Informatik David Doty and Benjamin L Lee and Tristan Stérin 2020 Is Part Of LIPIcs, Volume 174, 26th International Conference on DNA Computing and Molecular Programming (DNA 26) (2020) InProceedings Text doc-type:ResearchArticle publishedVersion application/pdf doi:10.4230/LIPIcs.DNA.2020.9 urn:nbn:de:0030-drops-129624 https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.DNA.2020.9 eng https://creativecommons.org/licenses/by/3.0/legalcode