2026-08-17T23:22:18Z https://drops.dagstuhl.de/oai

oai:drops-oai.dagstuhl.de:20645 2024-08-26T09:36:46Z ddc:004 open_access

Bioinformatics of Pathogens (Invited Talk) Vinař, Tomáš sequence analysis genome assembly neural networks probabilistic modeling Genomic sequencing has become an important tool in identification and surveillance of human pathogens. Compared to large organisms, where our goal is to obtain high-quality sequences for detailed analysis, in pathogen sequencing the emphasis is often on optimization of cost and time. Consequently, sequencing of pathogens creates interesting computational challenges and development of new methods has a potential to significantly enhance applicability of the results in epidemiology and clinical practice. In my talk, I will give two examples: plasmid identification in bacterial isolates and genomic surveillance of wastewater for SARS-CoV-2. In both cases, application of better algorithms and modeling helps to improve the quality of analysis of very noisy data. Schloss Dagstuhl – Leibniz-Zentrum für Informatik Tomáš Vinař 2024 Is Part Of LIPIcs, Volume 312, 24th International Workshop on Algorithms in Bioinformatics (WABI 2024) InProceedings Text doc-type:ResearchArticle publishedVersion application/pdf doi:10.4230/LIPIcs.WABI.2024.1 urn:nbn:de:0030-drops-206455 https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2024.1 eng https://creativecommons.org/licenses/by/4.0/legalcode