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Design Pillars for Medical Cyber-Physical System Middleware Arney, David Plourde, Jeff Schrenker, Rick Mattegunta, Pratyusha Whitehead, Susan F. Goldman, Julian M. Medical Device Interoperability Clinical Requirements Design Pillars Requirements Elicitation Validation Our goal is to improve patient outcomes and safety through medical device interoperability. To achieve this, it is not enough to build a technically perfect system. We present here our work toward the validation of middleware for use in interoperable medical cyber-physical systems. This includes clinical requirements, together with our methodology for collecting them, and a set of eighteen `design pillars' that document the non-functional requirements and design goals that we believe are necessary to build a successful interoperable medical device system. We discuss how the clinical requirements and design pillars are involved in the selection of a middleware for our OpenICE implementation. Schloss Dagstuhl – Leibniz-Zentrum für Informatik David Arney and Jeff Plourde and Rick Schrenker and Pratyusha Mattegunta and Susan F. Whitehead and Julian M. Goldman 2014 Is Part Of OASIcs, Volume 36, 5th Workshop on Medical Cyber-Physical Systems (2014) InProceedings Text doc-type:ResearchArticle publishedVersion application/pdf doi:10.4230/OASIcs.MCPS.2014.124 urn:nbn:de:0030-drops-45294 https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.MCPS.2014.124 eng https://creativecommons.org/licenses/by/3.0/legalcode