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        <datestamp>2024-03-06T10:43:01Z</datestamp>
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          <dc:title>A Succinct Four Russians Speedup for Edit Distance Computation and One-against-many Banded Alignment</dc:title>
          <dc:creator>Brubach, Brian</dc:creator>
          <dc:creator>Ghurye, Jay</dc:creator>
          <dc:subject>edit distance</dc:subject>
          <dc:subject>banded alignment</dc:subject>
          <dc:subject>one-against-many alignment</dc:subject>
          <dc:subject>genomics</dc:subject>
          <dc:subject>method of the Four Russians</dc:subject>
          <dc:description>The classical Four Russians speedup for computing edit distance (a.k.a. Levenshtein distance), due to Masek and Paterson [Masek and Paterson, 1980], involves partitioning the dynamic programming table into k-by-k square blocks and generating a lookup table in O(psi^{2k} k^2 |Sigma|^{2k}) time and O(psi^{2k} k |Sigma|^{2k}) space for block size k, where psi depends on the cost function (for unit costs psi = 3) and |Sigma| is the size of the alphabet. We show that the O(psi^{2k} k^2) and O(psi^{2k} k) factors can be improved to O(k^2 lg{k}) time and O(k^2) space. Thus, we improve the time and space complexity of that aspect compared to Masek and Paterson [Masek and Paterson, 1980] and remove the dependence on psi.
We further show that for certain problems the O(|Sigma|^{2k}) factor can also be reduced. Using this technique, we show a new algorithm for the fundamental problem of one-against-many banded alignment. In particular, comparing one string of length m to n other strings of length m with maximum distance d can be performed in O(n m + m d^2 lg{d} + n d^3) time. When d is reasonably small, this approaches or meets the current best theoretic result of O(nm + n d^2) achieved by using the best known pairwise algorithm running in O(m + d^2) time [Myers, 1986][Ukkonen, 1985] while potentially being more practical. It also improves on the standard practical approach which requires O(n m d) time to iteratively run an O(md) time pairwise banded alignment algorithm.
Regarding pairwise comparison, we extend the classic result of Masek and Paterson [Masek and Paterson, 1980] which computes the edit distance between two strings in O(m^2/log{m}) time to remove the dependence on psi even when edits have arbitrary costs from a penalty matrix. Crochemore, Landau, and Ziv-Ukelson [Crochemore, 2003] achieved a similar result, also allowing for unrestricted scoring matrices, but with variable-sized blocks. In practical applications of the Four Russians speedup wherein space efficiency is important and smaller block sizes k are used (notably k &lt; |Sigma|), Kim, Na, Park, and Sim [Kim et al., 2016] showed how to remove the dependence on the alphabet size for the unit cost version, generating a lookup table in O(3^{2k} (2k)! k^2) time and O(3^{2k} (2k)! k) space. Combining their work with our result yields an improvement to O((2k)! k^2 lg{k}) time and O((2k)! k^2) space.</dc:description>
          <dc:publisher>Schloss Dagstuhl – Leibniz-Zentrum für Informatik</dc:publisher>
          <dc:contributor>Brian Brubach and Jay Ghurye</dc:contributor>
          <dc:date>2018</dc:date>
          <dc:relation>Is Part Of LIPIcs, Volume 105, 29th Annual Symposium on Combinatorial Pattern Matching (CPM 2018)</dc:relation>
          <dc:type>InProceedings</dc:type>
          <dc:type>Text</dc:type>
          <dc:type>doc-type:ResearchArticle</dc:type>
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          <dc:identifier>doi:10.4230/LIPIcs.CPM.2018.13</dc:identifier>
          <dc:identifier>urn:nbn:de:0030-drops-86965</dc:identifier>
          <dc:identifier>https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2018.13</dc:identifier>
          <dc:language>eng</dc:language>
          <dc:rights>https://creativecommons.org/licenses/by/3.0/legalcode</dc:rights>
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