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Documents authored by Vandin, Fabio

Document
Complete Volume
DOI: 10.4230/LIPIcs.WABI.2026
LIPIcs, Volume 390, WABI 2026, Complete Volume

Authors: Nadia El-Mabrouk and Fabio Vandin

Published in: LIPIcs, Volume 390, 26th International Conference on Algorithms for Bioinformatics (WABI 2026)

Abstract
LIPIcs, Volume 390, WABI 2026, Complete Volume
Cite as

26th International Conference on Algorithms for Bioinformatics (WABI 2026). Leibniz International Proceedings in Informatics (LIPIcs), Volume 390, pp. 1-614, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2026)

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@Proceedings{elmabrouk_et_al:LIPIcs.WABI.2026,
  title =	{{LIPIcs, Volume 390, WABI 2026, Complete Volume}},
  booktitle =	{26th International Conference on Algorithms for Bioinformatics (WABI 2026)},
  pages =	{1--618},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-446-8},
  ISSN =	{1868-8969},
  year =	{2026},
  volume =	{390},
  editor =	{El-Mabrouk, Nadia and Vandin, Fabio},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2026},
  URN =		{urn:nbn:de:0030-drops-276955},
  doi =		{10.4230/LIPIcs.WABI.2026},
  annote =	{Keywords: LIPIcs, Volume 390, WABI 2026, Complete Volume}
}
Document
Front Matter
DOI: 10.4230/LIPIcs.WABI.2026.0
Front Matter, Table of Contents, Preface, Conference Organization

Authors: Nadia El-Mabrouk and Fabio Vandin

Published in: LIPIcs, Volume 390, 26th International Conference on Algorithms for Bioinformatics (WABI 2026)

Abstract
Front Matter, Table of Contents, Preface, Conference Organization
Cite as

26th International Conference on Algorithms for Bioinformatics (WABI 2026). Leibniz International Proceedings in Informatics (LIPIcs), Volume 390, pp. 0:i-0:xviii, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2026)

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@InProceedings{elmabrouk_et_al:LIPIcs.WABI.2026.0,
  author =	{El-Mabrouk, Nadia and Vandin, Fabio},
  title =	{{Front Matter, Table of Contents, Preface, Conference Organization}},
  booktitle =	{26th International Conference on Algorithms for Bioinformatics (WABI 2026)},
  pages =	{0:i--0:xviii},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-446-8},
  ISSN =	{1868-8969},
  year =	{2026},
  volume =	{390},
  editor =	{El-Mabrouk, Nadia and Vandin, Fabio},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2026.0},
  URN =		{urn:nbn:de:0030-drops-276935},
  doi =		{10.4230/LIPIcs.WABI.2026.0},
  annote =	{Keywords: Front Matter, Table of Contents, Preface, Conference Organization}
}
Document
DOI: 10.4230/LIPIcs.WABI.2018.18
Differentially Mutated Subnetworks Discovery

Authors: Morteza Chalabi Hajkarim, Eli Upfal, and Fabio Vandin

Published in: LIPIcs, Volume 113, 18th International Workshop on Algorithms in Bioinformatics (WABI 2018)

Abstract
We study the problem of identifying differentially mutated subnetworks of a large gene-gene interaction network, that is, subnetworks that display a significant difference in mutation frequency in two sets of cancer samples. We formally define the associated computational problem and show that the problem is NP-hard. We propose a novel and efficient algorithm, called DAMOKLE to identify differentially mutated subnetworks given genome-wide mutation data for two sets of cancer samples. We prove that DAMOKLE identifies subnetworks with a statistically significant difference in mutation frequency when the data comes from a reasonable generative model, provided enough samples are available. We test DAMOKLE on simulated and real data, showing that DAMOKLE does indeed find subnetworks with significant differences in mutation frequency and that it provides novel insights not obtained by standard methods.
Cite as

Morteza Chalabi Hajkarim, Eli Upfal, and Fabio Vandin. Differentially Mutated Subnetworks Discovery. In 18th International Workshop on Algorithms in Bioinformatics (WABI 2018). Leibniz International Proceedings in Informatics (LIPIcs), Volume 113, pp. 18:1-18:14, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2018)

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@InProceedings{hajkarim_et_al:LIPIcs.WABI.2018.18,
  author =	{Hajkarim, Morteza Chalabi and Upfal, Eli and Vandin, Fabio},
  title =	{{Differentially Mutated Subnetworks Discovery}},
  booktitle =	{18th International Workshop on Algorithms in Bioinformatics (WABI 2018)},
  pages =	{18:1--18:14},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-082-8},
  ISSN =	{1868-8969},
  year =	{2018},
  volume =	{113},
  editor =	{Parida, Laxmi and Ukkonen, Esko},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2018.18},
  URN =		{urn:nbn:de:0030-drops-93202},
  doi =		{10.4230/LIPIcs.WABI.2018.18},
  annote =	{Keywords: Cancer genomics, network analysis, combinatorial algorithm}
}

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