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DOI: 10.4230/LIPIcs.ICLP.2010.2
URN: urn:nbn:de:0030-drops-25776
URL: http://drops.dagstuhl.de/opus/volltexte/2010/2577/
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Fages, François

A Logical Paradigm for Systems Biology (Invited Talk)

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Abstract

Biologists use diagrams to represent complex systems of interaction between molecular species. These graphical notations encompass two types of information: interactions (e.g. protein complexation, modification, binding to a gene, etc.) and regulations (of an interaction or a transcription). Based on these structures, mathematical models can be developed by equipping such molecular interaction networks with kinetic expressions leading to quantitative models of mainly two kinds: ordinary differential equations for a continuous interpretation of the kinetics and continuous-time Markov chains for a stochastic interpretation of the kinetics. Since 2002, we investigate the transposition of programming concepts and tools to the analysis of living processes at the cellular level.

BibTeX - Entry

@InProceedings{fages:LIPIcs:2010:2577,
  author =	{Fran{\c{c}}ois Fages},
  title =	{{A Logical Paradigm for Systems Biology (Invited Talk)}},
  booktitle =	{Technical Communications of the 26th International Conference on Logic Programming},
  pages =	{2--3},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-939897-17-0},
  ISSN =	{1868-8969},
  year =	{2010},
  volume =	{7},
  editor =	{Manuel Hermenegildo and Torsten Schaub},
  publisher =	{Schloss Dagstuhl--Leibniz-Zentrum fuer Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{http://drops.dagstuhl.de/opus/volltexte/2010/2577},
  URN =		{urn:nbn:de:0030-drops-25776},
  doi =		{http://dx.doi.org/10.4230/LIPIcs.ICLP.2010.2},
  annote =	{Keywords: temporal logic, model-checking, systems biology, hybrid systems}
}

Keywords: temporal logic, model-checking, systems biology, hybrid systems
Seminar: Technical Communications of the 26th International Conference on Logic Programming
Issue Date: 2010
Date of publication: 25.06.2010


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