Multiscale Spatial Computational Systems Biology (Dagstuhl Seminar 14481)

Authors David Gilbert, Monika Heiner, Koichi Takahashi, Adelinde M. Uhrmacher and all authors of the abstracts in this report



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Author Details

David Gilbert
Monika Heiner
Koichi Takahashi
Adelinde M. Uhrmacher
and all authors of the abstracts in this report

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David Gilbert, Monika Heiner, Koichi Takahashi, and Adelinde M. Uhrmacher. Multiscale Spatial Computational Systems Biology (Dagstuhl Seminar 14481). In Dagstuhl Reports, Volume 4, Issue 11, pp. 138-226, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2015)
https://doi.org/10.4230/DagRep.4.11.138

Abstract

This report documents the program and the outcomes of Dagstuhl Seminar 14481 "Multiscale Spatial Computational Systems Biology". This seminar explored challenges arising from the need to model and analyse complex biological systems at multiple scales (spatial and temporal), which falls within the general remit of Computational Systems Biology. A distinguishing factor of the seminar was the modelling exercise -- where teams explored different modelling paradigms, in order to better understand the details of the approaches, their challenges, potential applications, and their pros and cons. This activity was carried out in a collaborative and self-directed manner using the Open Space Technology approach as evidenced by a high degree of communication both within and between the teams. Eight teams were formed, and reports from five of them are included in this document.
Keywords
  • Multiscale
  • multidimensional
  • computational modelling
  • space
  • time
  • systems biology
  • synthetic biology

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