Whelk: An OWL EL+RL Reasoner Enabling New Use Cases

Authors James P. Balhoff , Christopher J. Mungall



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Author Details

James P. Balhoff
  • Renaissance Computing Institute, University of North Carolina, Chapel Hill, NC, USA
Christopher J. Mungall
  • Lawrence Berkeley National Laboratory, Berkeley, CA, USA

Acknowledgements

We would like to thank N.L. Harris for helpful comments on a draft of the paper.

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James P. Balhoff and Christopher J. Mungall. Whelk: An OWL EL+RL Reasoner Enabling New Use Cases. In Special Issue on Resources for Graph Data and Knowledge. Transactions on Graph Data and Knowledge (TGDK), Volume 2, Issue 2, pp. 7:1-7:17, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2024) https://doi.org/10.4230/TGDK.2.2.7

Abstract

Many tasks in the biosciences rely on reasoning with large OWL terminologies (Tboxes), often combined with even larger databases. In particular, a common task is retrieval queries that utilize relational expressions; for example, “find all genes expressed in the brain or any part of the brain”. Automated reasoning on these ontologies typically relies on scalable reasoners targeting the EL subset of OWL, such as ELK. While the introduction of ELK has been transformative in the incorporation of reasoning into bio-ontology quality control and production pipelines, we have encountered limitations when applying it to use cases involving high throughput query answering or reasoning about datasets describing instances (Aboxes).
Whelk is a fast OWL reasoner for combined EL+RL reasoning. As such, it is particularly useful for many biological ontology tasks, particularly those characterized by large Tboxes using the EL subset of OWL, combined with Aboxes targeting the RL subset of OWL. Whelk is implemented in Scala and utilizes immutable functional data structures, which provides advantages when performing incremental or dynamic reasoning tasks. Whelk supports querying complex class expressions at a substantially greater rate than ELK, and can answer queries or perform incremental reasoning tasks in parallel, enabling novel applications of OWL reasoning.

Subject Classification

ACM Subject Classification
  • Information systems → Web Ontology Language (OWL)
  • Software and its engineering → Software libraries and repositories
  • Applied computing → Life and medical sciences
Keywords
  • Web Ontology Language
  • OWL
  • Semantic Web
  • ontology
  • reasoner

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References

  1. Konrad Abicht. Owl reasoners still useable in 2023, 2023. URL: https://doi.org/10.48550/arXiv.2309.06888.
  2. Franz Baader, Diego Calvanese, Deborah L. McGuinness, Daniele Nardi, and Peter F. Patel-Schneider, editors. The Description Logic Handbook: Theory, Implementation and Applications. Cambridge University Press, 2 edition, 2007. Google Scholar
  3. J Balhoff, Ugur Bayindir, Anita R Caron, N Matentzoglu, David Osumi-Sutherland, and C Mungall. Ubergraph: integrating OBO ontologies into a unified semantic graph. In ICBO 2022: International Conference on Biomedical Ontology (ICBO), 2022. URL: https://doi.org/10.5281/zenodo.7249759.
  4. J Balhoff, Benjamin M Good, S Carbon, and C Mungall. Arachne: An OWL RL reasoner applied to gene ontology causal activity models (and beyond). In 17th International Semantic Web Conference (ISWC 2018), October 2018. URL: https://doi.org/10.5281/zenodo.2397192.
  5. James P Balhoff. owlery: Owlery is a set of REST web services which allow querying of an OWL reasoner containing a configured set of ontologies. Accessed: 2024-6-29. URL: https://github.com/phenoscape/owlery.
  6. James P Balhoff. whelk-rs: Whelk is an OWL EL reasoner. Accessed: 2024-6-29. URL: https://github.com/INCATools/whelk-rs.
  7. James P. Balhoff. Incatools/whelk-paper, October 2024. Software, v1.1.0. URL: https://doi.org/10.5281/zenodo.13891879.
  8. James P Balhoff and Christopher J Mungall. boomer: Bayesian OWL ontology merging. Accessed: 2024-6-29. URL: https://github.com/INCATools/boomer.
  9. James P. Balhoff and Christopher J. Mungall. Whelk reasoner. Software, version 1.2.1., (visited on 2024-12-10). URL: https://github.com/INCATools/whelk
    Software Heritage Logo archived version
    full metadata available at: https://doi.org/10.4230/artifacts.22615
  10. Katy Börner, Sarah A Teichmann, Ellen M Quardokus, James C Gee, Kristen Browne, David Osumi-Sutherland, Bruce W Herr, 2nd, Andreas Bueckle, Hrishikesh Paul, Muzlifah Haniffa, Laura Jardine, Amy Bernard, Song-Lin Ding, Jeremy A Miller, Shin Lin, Marc K Halushka, Avinash Boppana, Teri A Longacre, John Hickey, Yiing Lin, M Todd Valerius, Yongqun He, Gloria Pryhuber, Xin Sun, Marda Jorgensen, Andrea J Radtke, Clive Wasserfall, Fiona Ginty, Jonhan Ho, Joel Sunshine, Rebecca T Beuschel, Maigan Brusko, Sujin Lee, Rajeev Malhotra, Sanjay Jain, and Griffin Weber. Anatomical structures, cell types and biomarkers of the human reference atlas. Nature cell biology, 23(11):1117-1128, November 2021. URL: https://doi.org/10.1038/s41556-021-00788-6.
  11. Openllet code repository. openllet: Openllet is an OWL 2 reasoner in java, build on top of pellet. Accessed: 2024-6-29. URL: https://github.com/Galigator/openllet.
  12. Alexander D Diehl, Terrence F Meehan, Yvonne M Bradford, Matthew H Brush, Wasila M Dahdul, David S Dougall, Yongqun He, David Osumi-Sutherland, Alan Ruttenberg, Sirarat Sarntivijai, Ceri E Van Slyke, Nicole A Vasilevsky, Melissa A Haendel, Judith A Blake, and Christopher J Mungall. The cell ontology 2016: enhanced content, modularization, and ontology interoperability. Journal of biomedical semantics, 7(1):44, July 2016. URL: https://doi.org/10.1186/s13326-016-0088-7.
  13. Robert B Doorenbos. Production Matching for Large Learning Systems. PhD thesis, Carnegie Mellon University, 1995. URL: http://reports-archive.adm.cs.cmu.edu/anon/1995/CMU-CS-95-113.pdf.
  14. ELK code repository. Elk: Owl features. Accessed: 2024-10-04. URL: https://github.com/liveontologies/elk-reasoner/wiki/OwlFeatures.
  15. Charles L Forgy. Rete: A fast algorithm for the many pattern/many object pattern match problem. Artificial intelligence, 19(1):17-37, September 1982. URL: https://doi.org/10.1016/0004-3702(82)90020-0.
  16. Michael A Gargano, Nicolas Matentzoglu, Ben Coleman, Eunice B Addo-Lartey, Anna V Anagnostopoulos, Joel Anderton, Paul Avillach, Anita M Bagley, Eduard Bakštein, James P Balhoff, Gareth Baynam, Susan M Bello, Michael Berk, Holli Bertram, Somer Bishop, Hannah Blau, David F Bodenstein, Pablo Botas, Kaan Boztug, Jolana Čady, Tiffany J Callahan, Rhiannon Cameron, Seth J Carbon, Francisco Castellanos, J Harry Caufield, Lauren E Chan, Christopher G Chute, Jaime Cruz-Rojo, Noémi Dahan-Oliel, Jon R Davids, Maud de Dieuleveult, Vinicius de Souza, Bert B A de Vries, Esther de Vries, J Raymond DePaulo, Beata Derfalvi, Ferdinand Dhombres, Claudia Diaz-Byrd, Alexander J M Dingemans, Bruno Donadille, Michael Duyzend, Reem Elfeky, Shahim Essaid, Carolina Fabrizzi, Giovanna Fico, Helen V Firth, Yun Freudenberg-Hua, Janice M Fullerton, Davera L Gabriel, Kimberly Gilmour, Jessica Giordano, Fernando S Goes, Rachel Gore Moses, Ian Green, Matthias Griese, Tudor Groza, Weihong Gu, Julia Guthrie, Benjamin Gyori, Ada Hamosh, Marc Hanauer, Kateřina Hanušová, Yongqun Oliver He, Harshad Hegde, Ingo Helbig, Kateřina Holasová, Charles Tapley Hoyt, Shangzhi Huang, Eric Hurwitz, Julius O B Jacobsen, Xiaofeng Jiang, Lisa Joseph, Kamyar Keramatian, Bryan King, Katrin Knoflach, David A Koolen, Megan L Kraus, Carlo Kroll, Maaike Kusters, Markus S Ladewig, David Lagorce, Meng-Chuan Lai, Pablo Lapunzina, Bryan Laraway, David Lewis-Smith, Xiarong Li, Caterina Lucano, Marzieh Majd, Mary L Marazita, Victor Martinez-Glez, Toby H McHenry, Melvin G McInnis, Julie A McMurry, Michaela Mihulová, Caitlin E Millett, Philip B Mitchell, Veronika Moslerová, Kenji Narutomi, Shahrzad Nematollahi, Julian Nevado, Andrew A Nierenberg, Nikola Novák Čajbiková, John I Nurnberger, Jr, Soichi Ogishima, Daniel Olson, Abigail Ortiz, Harry Pachajoa, Guiomar Perez de Nanclares, Amy Peters, Tim Putman, Christina K Rapp, Ana Rath, Justin Reese, Lauren Rekerle, Angharad M Roberts, Suzy Roy, Stephan J Sanders, Catharina Schuetz, Eva C Schulte, Thomas G Schulze, Martin Schwarz, Katie Scott, Dominik Seelow, Berthold Seitz, Yiping Shen, Morgan N Similuk, Eric S Simon, Balwinder Singh, Damian Smedley, Cynthia L Smith, Jake T Smolinsky, Sarah Sperry, Elizabeth Stafford, Ray Stefancsik, Robin Steinhaus, Rebecca Strawbridge, Jagadish Chandrabose Sundaramurthi, Polina Talapova, Jair A Tenorio Castano, Pavel Tesner, Rhys H Thomas, Audrey Thurm, Marek Turnovec, Marielle E van Gijn, Nicole A Vasilevsky, Markéta Vlčková, Anita Walden, Kai Wang, Ron Wapner, James S Ware, Addo A Wiafe, Samuel A Wiafe, Lisa D Wiggins, Andrew E Williams, Chen Wu, Margot J Wyrwoll, Hui Xiong, Nefize Yalin, Yasunori Yamamoto, Lakshmi N Yatham, Anastasia K Yocum, Allan H Young, Zafer Yüksel, Peter P Zandi, Andreas Zankl, Ignacio Zarante, Miroslav Zvolský, Sabrina Toro, Leigh C Carmody, Nomi L Harris, Monica C Munoz-Torres, Daniel Danis, Christopher J Mungall, Sebastian Köhler, Melissa A Haendel, and Peter N Robinson. The human phenotype ontology in 2024: phenotypes around the world. Nucleic acids research, 52(D1):D1333-D1346, January 2024. URL: https://doi.org/10.1093/nar/gkad1005.
  17. Gene Ontology Consortium, Suzi A Aleksander, James Balhoff, Seth Carbon, J Michael Cherry, Harold J Drabkin, Dustin Ebert, Marc Feuermann, Pascale Gaudet, Nomi L Harris, David P Hill, Raymond Lee, Huaiyu Mi, Sierra Moxon, Christopher J Mungall, Anushya Muruganugan, Tremayne Mushayahama, Paul W Sternberg, Paul D Thomas, Kimberly Van Auken, Jolene Ramsey, Deborah A Siegele, Rex L Chisholm, Petra Fey, Maria Cristina Aspromonte, Maria Victoria Nugnes, Federica Quaglia, Silvio Tosatto, Michelle Giglio, Suvarna Nadendla, Giulia Antonazzo, Helen Attrill, Gil Dos Santos, Steven Marygold, Victor Strelets, Christopher J Tabone, Jim Thurmond, Pinglei Zhou, Saadullah H Ahmed, Praoparn Asanitthong, Diana Luna Buitrago, Meltem N Erdol, Matthew C Gage, Mohamed Ali Kadhum, Kan Yan Chloe Li, Miao Long, Aleksandra Michalak, Angeline Pesala, Armalya Pritazahra, Shirin C C Saverimuttu, Renzhi Su, Kate E Thurlow, Ruth C Lovering, Colin Logie, Snezhana Oliferenko, Judith Blake, Karen Christie, Lori Corbani, Mary E Dolan, Harold J Drabkin, David P Hill, Li Ni, Dmitry Sitnikov, Cynthia Smith, Alayne Cuzick, James Seager, Laurel Cooper, Justin Elser, Pankaj Jaiswal, Parul Gupta, Pankaj Jaiswal, Sushma Naithani, Manuel Lera-Ramirez, Kim Rutherford, Valerie Wood, Jeffrey L De Pons, Melinda R Dwinell, G Thomas Hayman, Mary L Kaldunski, Anne E Kwitek, Stanley J F Laulederkind, Marek A Tutaj, Mahima Vedi, Shur-Jen Wang, Peter D'Eustachio, Lucila Aimo, Kristian Axelsen, Alan Bridge, Nevila Hyka-Nouspikel, Anne Morgat, Suzi A Aleksander, J Michael Cherry, Stacia R Engel, Kalpana Karra, Stuart R Miyasato, Robert S Nash, Marek S Skrzypek, Shuai Weng, Edith D Wong, Erika Bakker, Tanya Z Berardini, Leonore Reiser, Andrea Auchincloss, Kristian Axelsen, Ghislaine Argoud-Puy, Marie-Claude Blatter, Emmanuel Boutet, Lionel Breuza, Alan Bridge, Cristina Casals-Casas, Elisabeth Coudert, Anne Estreicher, Maria Livia Famiglietti, Marc Feuermann, Arnaud Gos, Nadine Gruaz-Gumowski, Chantal Hulo, Nevila Hyka-Nouspikel, Florence Jungo, Philippe Le Mercier, Damien Lieberherr, Patrick Masson, Anne Morgat, Ivo Pedruzzi, Lucille Pourcel, Sylvain Poux, Catherine Rivoire, Shyamala Sundaram, Alex Bateman, Emily Bowler-Barnett, Hema Bye-A-Jee, Paul Denny, Alexandr Ignatchenko, Rizwan Ishtiaq, Antonia Lock, Yvonne Lussi, Michele Magrane, Maria J Martin, Sandra Orchard, Pedro Raposo, Elena Speretta, Nidhi Tyagi, Kate Warner, Rossana Zaru, Alexander D Diehl, Raymond Lee, Juancarlos Chan, Stavros Diamantakis, Daniela Raciti, Magdalena Zarowiecki, Malcolm Fisher, Christina James-Zorn, Virgilio Ponferrada, Aaron Zorn, Sridhar Ramachandran, Leyla Ruzicka, and Monte Westerfield. The gene ontology knowledgebase in 2023. Genetics, 224(1), May 2023. URL: https://doi.org/10.1093/genetics/iyad031.
  18. Birte Glimm, Ian Horrocks, Boris Motik, Giorgos Stoilos, and Zhe Wang. HermiT: An OWL 2 reasoner. Journal of Automated Reasoning, 53(3):245-269, October 2014. URL: https://doi.org/10.1007/s10817-014-9305-1.
  19. Bruce W Herr, 2nd, Josef Hardi, Ellen M Quardokus, Andreas Bueckle, Lu Chen, Fusheng Wang, Anita R Caron, David Osumi-Sutherland, Mark A Musen, and Katy Börner. Specimen, biological structure, and spatial ontologies in support of a human reference atlas. Scientific data, 10(1):171, March 2023. URL: https://doi.org/10.1038/s41597-023-01993-8.
  20. Matthew Horridge and Sean Bechhofer. The OWL API: A java API for OWL ontologies. Semantic Web, 2(1):11-21, 2011. URL: https://doi.org/10.3233/SW-2011-0025.
  21. Ian Horrocks, Peter F Patel-Schneider, Harold Boley, Said Tabet, Benjamin Grosof, and Mike Dean. SWRL: A semantic web rule language combining OWL and RuleML. URL: https://www.w3.org/Submission/SWRL/.
  22. SNOMED International. SNOMED international. Accessed: 2024-6-27. URL: https://www.snomed.org/.
  23. Rebecca C Jackson, James P Balhoff, Eric Douglass, Nomi L Harris, Christopher J Mungall, and James A Overton. ROBOT: A tool for automating ontology workflows. BMC bioinformatics, 20(1):407, July 2019. URL: https://doi.org/10.1186/s12859-019-3002-3.
  24. Yevgeny Kazakov, Markus Krötzsch, and František Simančík. The incredible ELK. Journal of Automated Reasoning, 53(1):1-61, November 2013. URL: https://doi.org/10.1007/s10817-013-9296-3.
  25. Adila Krisnadhi, Frederick Maier, and Pascal Hitzler. OWL and rules. In Axel Polleres, Claudia d'Amato, Marcelo Arenas, Siegfried Handschuh, Paula Kroner, Sascha Ossowski, and Peter Patel-Schneider, editors, Reasoning Web. Semantic Technologies for the Web of Data: 7th International Summer School 2011, Galway, Ireland, August 23-27, 2011, Tutorial Lectures, pages 382-415. Springer Berlin Heidelberg, Berlin, Heidelberg, 2011. URL: https://doi.org/10.1007/978-3-642-23032-5_7.
  26. Phil Lord. horned-owl. Accessed: 2024-6-30. URL: https://github.com/phillord/horned-owl.
  27. Nicolas Matentzoglu, Damien Goutte-Gattat, Shawn Zheng Kai Tan, James P Balhoff, Seth Carbon, Anita R Caron, William D Duncan, Joe E Flack, Melissa Haendel, Nomi L Harris, William R Hogan, Charles Tapley Hoyt, Rebecca C Jackson, Hyeongsik Kim, Huseyin Kir, Martin Larralde, Julie A McMurry, James A Overton, Bjoern Peters, Clare Pilgrim, Ray Stefancsik, Sofia Mc Robb, Sabrina Toro, Nicole A Vasilevsky, Ramona Walls, Christopher J Mungall, and David Osumi-Sutherland. Ontology development kit: a toolkit for building, maintaining and standardizing biomedical ontologies. Database: the journal of biological databases and curation, 2022, October 2022. URL: https://doi.org/10.1093/database/baac087.
  28. C J Mungall, H Dietze, and D Osumi-Sutherland. Use of OWL within the gene ontology. In Maria Keet and Valentina Tamma, editors, Proceedings of the 11th International Workshop on OWL: Experiences and Directions (OWLED 2014), pages 25-36, Riva del Garda, Italy, October 17-18, 2014, October 2014. URL: https://doi.org/10.1101/010090.
  29. Christopher J Mungall, Sebastian Koehler, Peter Robinson, Ian Holmes, and Melissa Haendel. k-BOOM: A bayesian approach to ontology structure inference, with applications in disease ontology construction, May 2016. URL: https://doi.org/10.1101/048843.
  30. Christopher J Mungall, Carlo Torniai, Georgios V Gkoutos, Suzanna E Lewis, and Melissa A Haendel. Uberon, an integrative multi-species anatomy ontology. Genome biology, 13(1):R5, January 2012. URL: https://doi.org/10.1186/gb-2012-13-1-r5.
  31. Mark A Musen and Protégé Team. The protégé project: A look back and a look forward. AI matters, 1(4):4-12, June 2015. URL: https://doi.org/10.1145/2757001.2757003.
  32. Chris Okasaki. Purely Functional Data Structures. PhD thesis, Carnegie Mellon University, 1996. URL: https://www.cs.cmu.edu/~rwh/students/okasaki.pdf.
  33. Tim E Putman, Kevin Schaper, Nicolas Matentzoglu, Vincent P Rubinetti, Faisal S Alquaddoomi, Corey Cox, J Harry Caufield, Glass Elsarboukh, Sarah Gehrke, Harshad Hegde, Justin T Reese, Ian Braun, Richard M Bruskiewich, Luca Cappelletti, Seth Carbon, Anita R Caron, Lauren E Chan, Christopher G Chute, Katherina G Cortes, Vinícius De Souza, Tommaso Fontana, Nomi L Harris, Emily L Hartley, Eric Hurwitz, Julius O B Jacobsen, Madan Krishnamurthy, Bryan J Laraway, James A McLaughlin, Julie A McMurry, Sierra A T Moxon, Kathleen R Mullen, Shawn T O'Neil, Kent A Shefchek, Ray Stefancsik, Sabrina Toro, Nicole A Vasilevsky, Ramona L Walls, Patricia L Whetzel, David Osumi-Sutherland, Damian Smedley, Peter N Robinson, Christopher J Mungall, Melissa A Haendel, and Monica C Munoz-Torres. The monarch initiative in 2024: an analytic platform integrating phenotypes, genes and diseases across species. Nucleic acids research, 52(D1):D938-D949, January 2024. URL: https://doi.org/10.1093/nar/gkad1082.
  34. Gunjan Singh, Sumit Bhatia, and Raghava Mutharaju. OWL2Bench: A benchmark for OWL 2 reasoners. In The Semantic Web - ISWC 2020, pages 81-96. Springer International Publishing, 2020. URL: https://doi.org/10.1007/978-3-030-62466-8_6.
  35. Nicholas Sioutos, Sherri de Coronado, Margaret W Haber, Frank W Hartel, Wen-Ling Shaiu, and Lawrence W Wright. NCI thesaurus: a semantic model integrating cancer-related clinical and molecular information. Journal of biomedical informatics, 40(1):30-43, February 2007. URL: https://doi.org/10.1016/j.jbi.2006.02.013.
  36. Barry Smith, Werner Ceusters, Bert Klagges, Jacob Köhler, Anand Kumar, Jane Lomax, Chris Mungall, Fabian Neuhaus, Alan L Rector, and Cornelius Rosse. Relations in biomedical ontologies. Genome biology, 6(5):R46, April 2005. URL: https://doi.org/10.1186/gb-2005-6-5-r46.
  37. Paul D Thomas, David P Hill, Huaiyu Mi, David Osumi-Sutherland, Kimberly Van Auken, Seth Carbon, James P Balhoff, Laurent-Philippe Albou, Benjamin Good, Pascale Gaudet, Suzanna E Lewis, and Christopher J Mungall. Gene ontology causal activity modeling (GO-CAM) moves beyond GO annotations to structured descriptions of biological functions and systems. Nature genetics, 51(10):1429-1433, October 2019. URL: https://doi.org/10.1038/s41588-019-0500-1.
  38. Santiago Timón-Reina, Mariano Rincón, Rafael Martínez-Tomás, Bjørn-Eivind Kirsebom, and Tormod Fladby. A knowledge graph framework for dementia research data. NATO Advanced Science Institutes series E: Applied sciences, 13(18):10497, September 2023. URL: https://doi.org/10.3390/app131810497.
  39. Nicole A Vasilevsky, Nicolas A Matentzoglu, Sabrina Toro, Joseph E Flack, IV, Harshad Hegde, Deepak R Unni, Gioconda F Alyea, Joanna S Amberger, Larry Babb, James P Balhoff, Taylor I Bingaman, Gully A Burns, Orion J Buske, Tiffany J Callahan, Leigh C Carmody, Paula Carrio Cordo, Lauren E Chan, George S Chang, Sean L Christiaens, Michel Dumontier, Laura E Failla, May J Flowers, H Alpha Garrett, Jr, Jennifer L Goldstein, Dylan Gration, Tudor Groza, Marc Hanauer, Nomi L Harris, Jason A Hilton, Daniel S Himmelstein, Charles Tapley Hoyt, Megan S Kane, Sebastian Köhler, David Lagorce, Abbe Lai, Martin Larralde, Antonia Lock, Irene López Santiago, Donna R Maglott, Adriana J Malheiro, Birgit H M Meldal, Monica C Munoz-Torres, Tristan H Nelson, Frank W Nicholas, David Ochoa, Daniel P Olson, Tudor I Oprea, David Osumi-Sutherland, Helen Parkinson, Zoë May Pendlington, Ana Rath, Heidi L Rehm, Lyubov Remennik, Erin R Riggs, Paola Roncaglia, Justyne E Ross, Marion F Shadbolt, Kent A Shefchek, Morgan N Similuk, Nicholas Sioutos, Damian Smedley, Rachel Sparks, Ray Stefancsik, Ralf Stephan, Andrea L Storm, Doron Stupp, Gregory S Stupp, Jagadish Chandrabose Sundaramurthi, Imke Tammen, Darin Tay, Courtney L Thaxton, Eloise Valasek, Jordi Valls-Margarit, Alex H Wagner, Danielle Welter, Patricia L Whetzel, Lori L Whiteman, Valerie Wood, Colleen H Xu, Andreas Zankl, Xingmin Aaron Zhang, Christopher G Chute, Peter N Robinson, Christopher J Mungall, Ada Hamosh, and Melissa A Haendel. Mondo: Unifying diseases for the world, by the world, April 2022. URL: https://doi.org/10.1101/2022.04.13.22273750.
  40. W3C OWL Working Group. Owl 2 web ontology language document overview (second edition). Accessed: 2024-10-04. URL: https://www.w3.org/TR/owl2-overview/.
  41. W3C OWL Working Group. Owl 2 web ontology language manchester syntax (second edition). Accessed: 2024-10-04. URL: https://www.w3.org/TR/owl2-manchester-syntax/.
  42. W3C OWL Working Group. OWL 2 web ontology language profiles (second edition). URL: https://www.w3.org/TR/owl2-profiles/.
  43. École Polytechnique Fédérale Lausanne (EPFL). Scala native. Accessed: 2024-6-25. URL: https://scala-native.org/.
  44. École Polytechnique Fédérale Lausanne (EPFL). The scala programming language. Accessed: 2024-6-30. URL: https://www.scala-lang.org/.
  45. École Polytechnique Fédérale Lausanne (EPFL). Scala.js. Accessed: 2024-6-25. URL: https://www.scala-js.org.
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