3 Search Results for "Rosen, Yohei M."

Document
DOI: 10.4230/LIPIcs.GD.2025.37
Show Me Your Best Side: Characteristics of User-Preferred Perspectives for 3D Graph Drawings

Authors: Lucas Joos, Gavin J. Mooney, Maximilian T. Fischer, Daniel A. Keim, Falk Schreiber, Helen C. Purchase, and Karsten Klein

Published in: LIPIcs, Volume 357, 33rd International Symposium on Graph Drawing and Network Visualization (GD 2025)

Abstract
The visual analysis of graphs in 3D has become increasingly popular, accelerated by the rise of immersive technology, such as augmented and virtual reality. Unlike 2D drawings, 3D graph layouts are highly viewpoint-dependent, making perspective selection critical for revealing structural and relational patterns. Despite its importance, there is limited empirical evidence guiding what constitutes an effective or preferred viewpoint from the user’s perspective. In this paper, we present a systematic investigation into user-preferred viewpoints in 3D graph visualisations. We conducted a controlled study with 23 participants in a virtual reality environment, where users selected their most and least preferred viewpoints for 36 different graphs varying in size and layout. From this data, enriched by qualitative feedback, we distil common strategies underlying viewpoint choice. We further analyse the alignment of user preferences with classical 2D aesthetic criteria (e.g., Crossings), 3D-specific measures (e.g., Node-Node Occlusion), and introduce a novel measure capturing the perceivability of a graph’s principal axes (Isometric Viewpoint Deviation). Our data-driven analysis indicates that Stress, Crossings, Gabriel Ratio, Edge-Node Overlap, and Isometric Viewpoint Deviation are key indicators of viewpoint preference. Beyond our findings, we contribute a publicly available dataset consisting of the graphs and computed aesthetic measures, supporting further research and the development of viewpoint evaluation measures for 3D graph drawing.
Cite as

Lucas Joos, Gavin J. Mooney, Maximilian T. Fischer, Daniel A. Keim, Falk Schreiber, Helen C. Purchase, and Karsten Klein. Show Me Your Best Side: Characteristics of User-Preferred Perspectives for 3D Graph Drawings. In 33rd International Symposium on Graph Drawing and Network Visualization (GD 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 357, pp. 37:1-37:19, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)

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@InProceedings{joos_et_al:LIPIcs.GD.2025.37,
  author =	{Joos, Lucas and Mooney, Gavin J. and Fischer, Maximilian T. and Keim, Daniel A. and Schreiber, Falk and Purchase, Helen C. and Klein, Karsten},
  title =	{{Show Me Your Best Side: Characteristics of User-Preferred Perspectives for 3D Graph Drawings}},
  booktitle =	{33rd International Symposium on Graph Drawing and Network Visualization (GD 2025)},
  pages =	{37:1--37:19},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-403-1},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{357},
  editor =	{Dujmovi\'{c}, Vida and Montecchiani, Fabrizio},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.GD.2025.37},
  URN =		{urn:nbn:de:0030-drops-250236},
  doi =		{10.4230/LIPIcs.GD.2025.37},
  annote =	{Keywords: Graph Aesthetics, Immersive 3D, Node-Link Diagrams, Empirical Evaluation}
}
Document
DOI: 10.4230/LIPIcs.WABI.2025.14
Human Readable Compression of GFA Paths Using Grammar-Based Code

Authors: Peter Heringer and Daniel Doerr

Published in: LIPIcs, Volume 344, 25th International Conference on Algorithms for Bioinformatics (WABI 2025)

Abstract
Pangenome graphs offer a compact and comprehensive representation of genomic diversity, improving tasks such as variant calling, genotyping, and other downstream analyses. Although the underlying graph structures scale sublinearly with the number of haplotypes, the widely used GFA file format suffers from rapidly growing file sizes due to the explicit and repetitive encoding of haplotype paths. In this work, we introduce an extension to the GFA format that enables efficient grammar-based compression of haplotype paths while retaining human readability. In addition, grammar-based encoding provides an efficient in-memory data structure that does not require decompression, but conversely improves the runtime of many computational tasks that involve haplotype comparisons. We present sqz, a method that makes use of the proposed format extension to encode haplotype paths using byte pair encoding, a grammar-based compression scheme. We evaluate sqz on recent human pangenome graphs from Heumos et al. and the Human Pangenome Reference Consortium (HPRC), comparing it to existing compressors bgzip, gbz, and sequitur. sqz scales sublinearly with the number of haplotypes in a pangenome graph and consistently achieves higher compression ratios than sequitur and up to 5 times better compression than bgzip in HPRC graphs and up to 10 times in the graph from Heumos et al.. When combined with bgzip, sqz matches or excels the compression ratio of gbz across all our datasets. These results demonstrate the potential of our proposed extension of the GFA format in reducing haplotype path redundancy and improving storage efficiency for pangenome graphs.
Cite as

Peter Heringer and Daniel Doerr. Human Readable Compression of GFA Paths Using Grammar-Based Code. In 25th International Conference on Algorithms for Bioinformatics (WABI 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 344, pp. 14:1-14:19, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)

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@InProceedings{heringer_et_al:LIPIcs.WABI.2025.14,
  author =	{Heringer, Peter and Doerr, Daniel},
  title =	{{Human Readable Compression of GFA Paths Using Grammar-Based Code}},
  booktitle =	{25th International Conference on Algorithms for Bioinformatics (WABI 2025)},
  pages =	{14:1--14:19},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-386-7},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{344},
  editor =	{Brejov\'{a}, Bro\v{n}a and Patro, Rob},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2025.14},
  URN =		{urn:nbn:de:0030-drops-239395},
  doi =		{10.4230/LIPIcs.WABI.2025.14},
  annote =	{Keywords: pangenomics, pangenome graphs, compression, grammar-based code, byte pair encoding}
}
Document
DOI: 10.4230/LIPIcs.WABI.2018.9
An Average-Case Sublinear Exact Li and Stephens Forward Algorithm

Authors: Yohei M. Rosen and Benedict J. Paten

Published in: LIPIcs, Volume 113, 18th International Workshop on Algorithms in Bioinformatics (WABI 2018)

Abstract
Hidden Markov models of haplotype inheritance such as the Li and Stephens model allow for computationally tractable probability calculations using the forward algorithms as long as the representative reference panel used in the model is sufficiently small. Specifically, the monoploid Li and Stephens model and its variants are linear in reference panel size unless heuristic approximations are used. However, sequencing projects numbering in the thousands to hundreds of thousands of individuals are underway, and others numbering in the millions are anticipated. To make the Li and Stephens forward algorithm for these datasets computationally tractable, we have created a numerically exact version of the algorithm with observed average case O(nk^{0.35}) runtime in number of genetic sites n and reference panel size k. This avoids any tradeoff between runtime and model complexity. We demonstrate that our approach also provides a succinct data structure for general purpose haplotype data storage. We discuss generalizations of our algorithmic techniques to other hidden Markov models.
Cite as

Yohei M. Rosen and Benedict J. Paten. An Average-Case Sublinear Exact Li and Stephens Forward Algorithm. In 18th International Workshop on Algorithms in Bioinformatics (WABI 2018). Leibniz International Proceedings in Informatics (LIPIcs), Volume 113, pp. 9:1-9:13, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2018)

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@InProceedings{rosen_et_al:LIPIcs.WABI.2018.9,
  author =	{Rosen, Yohei M. and Paten, Benedict J.},
  title =	{{An Average-Case Sublinear Exact Li and Stephens Forward Algorithm}},
  booktitle =	{18th International Workshop on Algorithms in Bioinformatics (WABI 2018)},
  pages =	{9:1--9:13},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-082-8},
  ISSN =	{1868-8969},
  year =	{2018},
  volume =	{113},
  editor =	{Parida, Laxmi and Ukkonen, Esko},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2018.9},
  URN =		{urn:nbn:de:0030-drops-93116},
  doi =		{10.4230/LIPIcs.WABI.2018.9},
  annote =	{Keywords: Haplotype, Hidden Markov Model, Forward Algorithm, Lazy Evaluation}
}
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