4 Search Results for "Tsujii, Jun'ichi"


Document
R-Enum Revisited: Speedup and Extension for Context-Sensitive Repeats and Net Frequencies

Authors: Kotaro Kimura and Tomohiro I

Published in: LIPIcs, Volume 369, 37th Annual Symposium on Combinatorial Pattern Matching (CPM 2026)


Abstract
A repeat is a substring that occurs at least twice in a string, and is called a maximal repeat if it cannot be extended outwards without reducing its frequency. Nishimoto and Tabei [CPM, 2021] proposed r-enum, an algorithm to enumerate various characteristic substrings, including maximal repeats, in a string T of length n in O(r) words of compressed working space, where r ≤ n is the number of runs in the Burrows-Wheeler transform (BWT) of T. Given the run-length encoded BWT (RLBWT) of T, r-enum runs in O(n log log_w (n/r)) time in addition to the time linear to the number of output strings, where w = Θ(log n) is the word size. In this paper, we first improve the O(n log log_w (n/r)) term to O(n). We next extend r-enum to compute other context-sensitive repeats such as near-supermaximal repeats (NSMRs) and supermaximal repeats, as well as the context diversity for every maximal repeat in the same complexities. Furthermore, we study net occurrences: An occurrence of a repeat is called a net occurrence if it is not covered by another repeat, and the net frequency of a repeat is the number of its net occurrences. With this terminology, an NSMR is a repeat with a positive net frequency. Given the RLBWT of T, we show how to compute the set 𝒮^{nsmr} of all NSMRs in T together with their net frequency/occurrences in O(n) time and O(r) space. We also show that an O(r)-space data structure can be built from the RLBWT to compute the net frequency/occurrences of any pattern in optimal time. The data structure is built in O(r) space and in O(n) time with high probability or deterministic O(n + |𝒮^{nsmr}| log log min(σ, |𝒮^{nsmr}|)) time, where σ ≤ r is the alphabet size of T. To achieve this, we prove that the total number of net occurrences is less than 2r. With the duality between net occurrences and minimal unique substrings (MUSs), we get a new upper bound 2r of the number of MUSs in T, which may be of independent interest.

Cite as

Kotaro Kimura and Tomohiro I. R-Enum Revisited: Speedup and Extension for Context-Sensitive Repeats and Net Frequencies. In 37th Annual Symposium on Combinatorial Pattern Matching (CPM 2026). Leibniz International Proceedings in Informatics (LIPIcs), Volume 369, pp. 10:1-10:14, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2026)


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@InProceedings{kimura_et_al:LIPIcs.CPM.2026.10,
  author =	{Kimura, Kotaro and I, Tomohiro},
  title =	{{R-Enum Revisited: Speedup and Extension for Context-Sensitive Repeats and Net Frequencies}},
  booktitle =	{37th Annual Symposium on Combinatorial Pattern Matching (CPM 2026)},
  pages =	{10:1--10:14},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-420-8},
  ISSN =	{1868-8969},
  year =	{2026},
  volume =	{369},
  editor =	{Bille, Philip and Prezza, Nicola},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2026.10},
  URN =		{urn:nbn:de:0030-drops-259361},
  doi =		{10.4230/LIPIcs.CPM.2026.10},
  annote =	{Keywords: Supermaximal repeats, Largest maximal repeats, Net frequencies, Run-length Burrows-Wheeler transform, Compressed data mining}
}
Document
Position
Knowledge Graphs for the Life Sciences: Recent Developments, Challenges and Opportunities

Authors: Jiaoyan Chen, Hang Dong, Janna Hastings, Ernesto Jiménez-Ruiz, Vanessa López, Pierre Monnin, Catia Pesquita, Petr Škoda, and Valentina Tamma

Published in: TGDK, Volume 1, Issue 1 (2023): Special Issue on Trends in Graph Data and Knowledge. Transactions on Graph Data and Knowledge, Volume 1, Issue 1


Abstract
The term life sciences refers to the disciplines that study living organisms and life processes, and include chemistry, biology, medicine, and a range of other related disciplines. Research efforts in life sciences are heavily data-driven, as they produce and consume vast amounts of scientific data, much of which is intrinsically relational and graph-structured. The volume of data and the complexity of scientific concepts and relations referred to therein promote the application of advanced knowledge-driven technologies for managing and interpreting data, with the ultimate aim to advance scientific discovery. In this survey and position paper, we discuss recent developments and advances in the use of graph-based technologies in life sciences and set out a vision for how these technologies will impact these fields into the future. We focus on three broad topics: the construction and management of Knowledge Graphs (KGs), the use of KGs and associated technologies in the discovery of new knowledge, and the use of KGs in artificial intelligence applications to support explanations (explainable AI). We select a few exemplary use cases for each topic, discuss the challenges and open research questions within these topics, and conclude with a perspective and outlook that summarizes the overarching challenges and their potential solutions as a guide for future research.

Cite as

Jiaoyan Chen, Hang Dong, Janna Hastings, Ernesto Jiménez-Ruiz, Vanessa López, Pierre Monnin, Catia Pesquita, Petr Škoda, and Valentina Tamma. Knowledge Graphs for the Life Sciences: Recent Developments, Challenges and Opportunities. In Special Issue on Trends in Graph Data and Knowledge. Transactions on Graph Data and Knowledge (TGDK), Volume 1, Issue 1, pp. 5:1-5:33, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2023)


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@Article{chen_et_al:TGDK.1.1.5,
  author =	{Chen, Jiaoyan and Dong, Hang and Hastings, Janna and Jim\'{e}nez-Ruiz, Ernesto and L\'{o}pez, Vanessa and Monnin, Pierre and Pesquita, Catia and \v{S}koda, Petr and Tamma, Valentina},
  title =	{{Knowledge Graphs for the Life Sciences: Recent Developments, Challenges and Opportunities}},
  journal =	{Transactions on Graph Data and Knowledge},
  pages =	{5:1--5:33},
  year =	{2023},
  volume =	{1},
  number =	{1},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/TGDK.1.1.5},
  URN =		{urn:nbn:de:0030-drops-194791},
  doi =		{10.4230/TGDK.1.1.5},
  annote =	{Keywords: Knowledge graphs, Life science, Knowledge discovery, Explainable AI}
}
Document
Survey
How Does Knowledge Evolve in Open Knowledge Graphs?

Authors: Axel Polleres, Romana Pernisch, Angela Bonifati, Daniele Dell'Aglio, Daniil Dobriy, Stefania Dumbrava, Lorena Etcheverry, Nicolas Ferranti, Katja Hose, Ernesto Jiménez-Ruiz, Matteo Lissandrini, Ansgar Scherp, Riccardo Tommasini, and Johannes Wachs

Published in: TGDK, Volume 1, Issue 1 (2023): Special Issue on Trends in Graph Data and Knowledge. Transactions on Graph Data and Knowledge, Volume 1, Issue 1


Abstract
Openly available, collaboratively edited Knowledge Graphs (KGs) are key platforms for the collective management of evolving knowledge. The present work aims t o provide an analysis of the obstacles related to investigating and processing specifically this central aspect of evolution in KGs. To this end, we discuss (i) the dimensions of evolution in KGs, (ii) the observability of evolution in existing, open, collaboratively constructed Knowledge Graphs over time, and (iii) possible metrics to analyse this evolution. We provide an overview of relevant state-of-the-art research, ranging from metrics developed for Knowledge Graphs specifically to potential methods from related fields such as network science. Additionally, we discuss technical approaches - and their current limitations - related to storing, analysing and processing large and evolving KGs in terms of handling typical KG downstream tasks.

Cite as

Axel Polleres, Romana Pernisch, Angela Bonifati, Daniele Dell'Aglio, Daniil Dobriy, Stefania Dumbrava, Lorena Etcheverry, Nicolas Ferranti, Katja Hose, Ernesto Jiménez-Ruiz, Matteo Lissandrini, Ansgar Scherp, Riccardo Tommasini, and Johannes Wachs. How Does Knowledge Evolve in Open Knowledge Graphs?. In Special Issue on Trends in Graph Data and Knowledge. Transactions on Graph Data and Knowledge (TGDK), Volume 1, Issue 1, pp. 11:1-11:59, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2023)


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@Article{polleres_et_al:TGDK.1.1.11,
  author =	{Polleres, Axel and Pernisch, Romana and Bonifati, Angela and Dell'Aglio, Daniele and Dobriy, Daniil and Dumbrava, Stefania and Etcheverry, Lorena and Ferranti, Nicolas and Hose, Katja and Jim\'{e}nez-Ruiz, Ernesto and Lissandrini, Matteo and Scherp, Ansgar and Tommasini, Riccardo and Wachs, Johannes},
  title =	{{How Does Knowledge Evolve in Open Knowledge Graphs?}},
  journal =	{Transactions on Graph Data and Knowledge},
  pages =	{11:1--11:59},
  year =	{2023},
  volume =	{1},
  number =	{1},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/TGDK.1.1.11},
  URN =		{urn:nbn:de:0030-drops-194855},
  doi =		{10.4230/TGDK.1.1.11},
  annote =	{Keywords: KG evolution, temporal KG, versioned KG, dynamic KG}
}
Document
Coreference Resolution in Biomedical Texts: a Machine Learning Approach

Authors: Jian Su, Xiaofeng Yang, Huaqing Hong, Yuka Tateisi, and Jun'ichi Tsujii

Published in: Dagstuhl Seminar Proceedings, Volume 8131, Ontologies and Text Mining for Life Sciences : Current Status and Future Perspectives (2008)


Abstract
Motivation: Coreference resolution, the process of identifying different mentions of an entity, is a very important component in a text-mining system. Compared with the work in news articles, the existing study of coreference resolution in biomedical texts is quite preliminary by only focusing on specific types of anaphors like pronouns or definite noun phrases, using heuristic methods, and running on small data sets. Therefore, there is a need for an in-depth exploration of this task in the biomedical domain. Results: In this article, we presented a learning-based approach to coreference resolution in the biomedical domain. We made three contributions in our study. Firstly, we annotated a large scale coreference corpus, MedCo, which consists of 1,999 medline abstracts in the GENIA data set. Secondly, we proposed a detailed framework for the coreference resolution task, in which we augmented the traditional learning model by incorporating non-anaphors into training. Lastly, we explored various sources of knowledge for coreference resolution, particularly, those that can deal with the complexity of biomedical texts. The evaluation on the MedCo corpus showed promising results. Our coreference resolution system achieved a high precision of 85.2% with a reasonable recall of 65.3%, obtaining an F-measure of 73.9%. The results also suggested that our augmented learning model significantly boosted precision (up to 24.0%) without much loss in recall (less than 5%), and brought a gain of over 8% in F-measure.

Cite as

Jian Su, Xiaofeng Yang, Huaqing Hong, Yuka Tateisi, and Jun'ichi Tsujii. Coreference Resolution in Biomedical Texts: a Machine Learning Approach. In Ontologies and Text Mining for Life Sciences : Current Status and Future Perspectives. Dagstuhl Seminar Proceedings, Volume 8131, p. 1, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2008)


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@InProceedings{su_et_al:DagSemProc.08131.4,
  author =	{Su, Jian and Yang, Xiaofeng and Hong, Huaqing and Tateisi, Yuka and Tsujii, Jun'ichi},
  title =	{{Coreference Resolution in Biomedical Texts: a Machine Learning Approach}},
  booktitle =	{Ontologies and Text Mining for Life Sciences : Current Status and Future Perspectives},
  pages =	{1--1},
  series =	{Dagstuhl Seminar Proceedings (DagSemProc)},
  ISSN =	{1862-4405},
  year =	{2008},
  volume =	{8131},
  editor =	{Michael Ashburner and Ulf Leser and Dietrich Rebholz-Schuhmann},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/DagSemProc.08131.4},
  URN =		{urn:nbn:de:0030-drops-15220},
  doi =		{10.4230/DagSemProc.08131.4},
  annote =	{Keywords: Coreference resolution, biomedical text}
}
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