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Documents authored by Riis-Nielson, Hanne

Document
DOI: 10.4230/DagSemProc.06161.1
06161 Abstracts Collection – Simulation and Verification of Dynamic Systems

Authors: David M. Nicol, Corrado Priami, Hanne Riis-Nielson, and Adelinde M. Uhrmacher

Published in: Dagstuhl Seminar Proceedings, Volume 6161, Simulation and Verification of Dynamic Systems (2006)

Abstract
From 17.04.06 to 22.04.06, the Dagstuhl Seminar 06161 ``Simulation and Verification of Dynamic Systems'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available.
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David M. Nicol, Corrado Priami, Hanne Riis-Nielson, and Adelinde M. Uhrmacher. 06161 Abstracts Collection – Simulation and Verification of Dynamic Systems. In Simulation and Verification of Dynamic Systems. Dagstuhl Seminar Proceedings, Volume 6161, pp. 1-13, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2006)

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@InProceedings{nicol_et_al:DagSemProc.06161.1,
  author =	{Nicol, David M. and Priami, Corrado and Riis-Nielson, Hanne and Uhrmacher, Adelinde M.},
  title =	{{06161 Abstracts Collection – Simulation and Verification of Dynamic Systems}},
  booktitle =	{Simulation and Verification of Dynamic Systems},
  pages =	{1--13},
  series =	{Dagstuhl Seminar Proceedings (DagSemProc)},
  ISSN =	{1862-4405},
  year =	{2006},
  volume =	{6161},
  editor =	{David M. Nicol and Corrado Priami and Hanne Riis Nielson and Adelinde M. Uhrmacher},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/DagSemProc.06161.1},
  URN =		{urn:nbn:de:0030-drops-7102},
  doi =		{10.4230/DagSemProc.06161.1},
  annote =	{Keywords: Modeling, Simulation, Verification, Dynamic Systems, Systemsbiology}
}
Document
DOI: 10.4230/DagSemProc.06161.6
Context Dependent Analysis of BioAmbients

Authors: Henrik Pilegaard, Hanne Riis-Nielson, and Flemming Nielson

Published in: Dagstuhl Seminar Proceedings, Volume 6161, Simulation and Verification of Dynamic Systems (2006)

Abstract
BioAmbients is a derivative of mobile ambients that has shown promise of describing interesting features of the behaviour of biological systems. The technical contribution of this paper is to extend the Flow Logic approach to static analysis with a couple of new techniques in order to give precise information about the behaviour of systems written in BioAmbients. Applying the development to a simple model of a cell releasing nutrients from food compunds we illustrate how the proposed analysis does indeed improve on previous efforts.
Cite as

Henrik Pilegaard, Hanne Riis-Nielson, and Flemming Nielson. Context Dependent Analysis of BioAmbients. In Simulation and Verification of Dynamic Systems. Dagstuhl Seminar Proceedings, Volume 6161, pp. 1-18, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2006)

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@InProceedings{pilegaard_et_al:DagSemProc.06161.6,
  author =	{Pilegaard, Henrik and Riis-Nielson, Hanne and Nielson, Flemming},
  title =	{{Context Dependent Analysis of BioAmbients}},
  booktitle =	{Simulation and Verification of Dynamic Systems},
  pages =	{1--18},
  series =	{Dagstuhl Seminar Proceedings (DagSemProc)},
  ISSN =	{1862-4405},
  year =	{2006},
  volume =	{6161},
  editor =	{David M. Nicol and Corrado Priami and Hanne Riis Nielson and Adelinde M. Uhrmacher},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/DagSemProc.06161.6},
  URN =		{urn:nbn:de:0030-drops-7093},
  doi =		{10.4230/DagSemProc.06161.6},
  annote =	{Keywords: Static analysis, abstract interpretation, BioAmbients}
}
Document
DOI: 10.4230/DagSemProc.06161.2
06161 Executive Summary – Simulation and Verification of Dynamic Systems

Authors: Hanne Riis-Nielson, David M. Nicol, Corrado Priami, and Adelinde M. Uhrmacher

Published in: Dagstuhl Seminar Proceedings, Volume 6161, Simulation and Verification of Dynamic Systems (2006)

Abstract
Simulation is widely used for modeling engineering artifacts and natural phenomena to gain insight into the operation of those systems. Formal verification is concerned with proving or disproving the correctness of a system with respect to a certain property. Despite of these different objectives, the fields of simulation and verification address similar research challenges. Particularly, in the application area systems biology simulation and verification are moving together. The Dagstuhl Seminar was dedicated to intensifying this dialogue, and stimulating the exchange of ideas. Three working groups discussed questions: Why are biological systems difficult to model?, What role does refinement and abstraction play in combining simulation and verification?, What is the role of communication and composition in simulating and analysing dynamic systems? The results of the working groups can be found in the working groups' report.
Cite as

Hanne Riis-Nielson, David M. Nicol, Corrado Priami, and Adelinde M. Uhrmacher. 06161 Executive Summary – Simulation and Verification of Dynamic Systems. In Simulation and Verification of Dynamic Systems. Dagstuhl Seminar Proceedings, Volume 6161, pp. 1-2, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2006)

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@InProceedings{riisnielson_et_al:DagSemProc.06161.2,
  author =	{Riis-Nielson, Hanne and Nicol, David M. and Priami, Corrado and Uhrmacher, Adelinde M.},
  title =	{{06161 Executive Summary – Simulation and Verification of Dynamic Systems}},
  booktitle =	{Simulation and Verification of Dynamic Systems},
  pages =	{1--2},
  series =	{Dagstuhl Seminar Proceedings (DagSemProc)},
  ISSN =	{1862-4405},
  year =	{2006},
  volume =	{6161},
  editor =	{David M. Nicol and Corrado Priami and Hanne Riis Nielson and Adelinde M. Uhrmacher},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/DagSemProc.06161.2},
  URN =		{urn:nbn:de:0030-drops-7028},
  doi =		{10.4230/DagSemProc.06161.2},
  annote =	{Keywords: Modelling, Simulation, Verification, Systemsbiology}
}
Document
DOI: 10.4230/DagSemProc.06161.9
Static Analysis of a Model of the LDL Degradation Pathway

Authors: Henrik Pilegaard, Hanne Riis-Nielson, and Flemming Nielson

Published in: Dagstuhl Seminar Proceedings, Volume 6161, Simulation and Verification of Dynamic Systems (2006)

Abstract
BioAmbients is a derivative of mobile ambients that has shown promise of describing interesting features of the behaviour of biological systems. As for other ambient calculi static program analysis can be used to compute safe approximations of the behaviour of system models. We use these tools to model and analyse the production of cholesterol in living cells and show that we are able to pinpoint the difference in behaviour between models of healthy systems and models of mutated systems giving rise to known diseases.
Cite as

Henrik Pilegaard, Hanne Riis-Nielson, and Flemming Nielson. Static Analysis of a Model of the LDL Degradation Pathway. In Simulation and Verification of Dynamic Systems. Dagstuhl Seminar Proceedings, Volume 6161, pp. 1-13, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2006)

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@InProceedings{pilegaard_et_al:DagSemProc.06161.9,
  author =	{Pilegaard, Henrik and Riis-Nielson, Hanne and Nielson, Flemming},
  title =	{{Static Analysis of a Model of the LDL Degradation Pathway}},
  booktitle =	{Simulation and Verification of Dynamic Systems},
  pages =	{1--13},
  series =	{Dagstuhl Seminar Proceedings (DagSemProc)},
  ISSN =	{1862-4405},
  year =	{2006},
  volume =	{6161},
  editor =	{David M. Nicol and Corrado Priami and Hanne Riis Nielson and Adelinde M. Uhrmacher},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/DagSemProc.06161.9},
  URN =		{urn:nbn:de:0030-drops-7230},
  doi =		{10.4230/DagSemProc.06161.9},
  annote =	{Keywords: Static analysis, Systems Biology, BioAmbients, LDL Degradation Pathway}
}
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