12 Search Results for "Baier, Uwe"


Document
Fast and Lightweight Distributed Suffix Array Construction

Authors: Manuel Haag, Florian Kurpicz, Peter Sanders, and Matthias Schimek

Published in: LIPIcs, Volume 351, 33rd Annual European Symposium on Algorithms (ESA 2025)


Abstract
The suffix array contains the lexicographical order of all suffixes of a text. It is one of the most well-studied text indices with applications in bioinformatics, compression, and pattern matching. The main bottleneck of distributed-memory suffix array construction algorithms is their memory requirements. Even careful implementations require 30×-60× the input size as working memory. We present a scalable and lightweight distributed-memory adaptation of the difference cover (DCX) suffix array construction algorithm. Our approach relies on novel bucketing and random chunk redistribution techniques which reduce our memory requirement to 20×-26× the input size for medium-sized inputs and to 14×-15× for large-sized inputs. Regarding running time, we achieve speedups of up to 5× over current state-of-the-art distributed suffix array construction algorithms.

Cite as

Manuel Haag, Florian Kurpicz, Peter Sanders, and Matthias Schimek. Fast and Lightweight Distributed Suffix Array Construction. In 33rd Annual European Symposium on Algorithms (ESA 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 351, pp. 47:1-47:18, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{haag_et_al:LIPIcs.ESA.2025.47,
  author =	{Haag, Manuel and Kurpicz, Florian and Sanders, Peter and Schimek, Matthias},
  title =	{{Fast and Lightweight Distributed Suffix Array Construction}},
  booktitle =	{33rd Annual European Symposium on Algorithms (ESA 2025)},
  pages =	{47:1--47:18},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-395-9},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{351},
  editor =	{Benoit, Anne and Kaplan, Haim and Wild, Sebastian and Herman, Grzegorz},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.ESA.2025.47},
  URN =		{urn:nbn:de:0030-drops-245154},
  doi =		{10.4230/LIPIcs.ESA.2025.47},
  annote =	{Keywords: Distributed Computing, Suffix Array Construction}
}
Document
Fast and Memory-Efficient BWT Construction of Repetitive Texts Using Lyndon Grammars

Authors: Jannik Olbrich

Published in: LIPIcs, Volume 351, 33rd Annual European Symposium on Algorithms (ESA 2025)


Abstract
The Burrows-Wheeler Transform (BWT) serves as the basis for many important sequence indexes. On very large datasets (e.g. genomic databases), classical BWT construction algorithms are often infeasible because they usually need to have the entire dataset in main memory. Fortunately, such large datasets are often highly repetitive. It can thus be beneficial to compute the BWT from a compressed representation. We propose an algorithm for computing the BWT via the Lyndon straight-line program, a grammar based on the standard factorization of Lyndon words. Our algorithm can also be used to compute the extended BWT (eBWT) of a multiset of sequences. We empirically evaluate our implementation and find that we can compute the BWT and eBWT of very large datasets faster and/or with less memory than competing methods.

Cite as

Jannik Olbrich. Fast and Memory-Efficient BWT Construction of Repetitive Texts Using Lyndon Grammars. In 33rd Annual European Symposium on Algorithms (ESA 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 351, pp. 60:1-60:19, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{olbrich:LIPIcs.ESA.2025.60,
  author =	{Olbrich, Jannik},
  title =	{{Fast and Memory-Efficient BWT Construction of Repetitive Texts Using Lyndon Grammars}},
  booktitle =	{33rd Annual European Symposium on Algorithms (ESA 2025)},
  pages =	{60:1--60:19},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-395-9},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{351},
  editor =	{Benoit, Anne and Kaplan, Haim and Wild, Sebastian and Herman, Grzegorz},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.ESA.2025.60},
  URN =		{urn:nbn:de:0030-drops-245286},
  doi =		{10.4230/LIPIcs.ESA.2025.60},
  annote =	{Keywords: Burrows-Wheeler Transform, Grammar compression}
}
Document
Invited Talk
We Are What We Index; a Primer for the Wheeler Graph Era (Invited Talk)

Authors: Ben Langmead

Published in: LIPIcs, Volume 344, 25th International Conference on Algorithms for Bioinformatics (WABI 2025)


Abstract
Since the arrival of second-generation sequencing, we have needed to build indexes over reference sequences - e.g. genomes and transcriptomes - in order to solve read alignment and classification problems efficiently [Langmead et al., 2009; Li and Durbin, 2009; Li et al., 2009]. The rule has been: what we can index determines what we can do. When indexing strings, we can use methods like suffix arrays [Manber and Myers, 1993], the Burrows-Wheeler Transform (BWT) [Burrows and Wheeler, 1994] / FM Index [Ferragina and Manzini, 2000], or k-mer indexes [Marchet et al., 2021]. What if we want to index objects more complex than strings? A pangenome, for example, is a large collection of similar strings, e.g. the hundreds of assemblies that make up the Human Pangenome Reference [Liao et al., 2023] or all the bacteria in the Refseq database [Goldfarb et al., 2025]. We may wish to combine these strings into a multiple sequence alignment (MSA) or a graph first. Can we index those efficiently? In many useful cases the answer is "yes," but in others the answer is "no." The story of how we learned exactly when the answer is "yes" versus "no" unfolded through a sequence of insights. Here we review this story, eventually arriving at the definition of Wheeler graphs as discovered and formalized by Gagie, Manzini and Sirén [Gagie et al., 2017]. We will focus on indexes based on the BWT, since these (a) are lossless full-text indexes, (b) are widely used in practice [Langmead et al., 2009; Li and Durbin, 2009], and (c) form the theoretical throughline for all the indexing strategies on the path to Wheeler graphs. We will trace the BWT-based indexing story from the early days of the FM Index, though its step-by-step gobbling up of trees (XBW-transform [Ferragina et al., 2005]) and de Bruijn Graphs (BOSS representation [Bowe et al., 2012]), and to the eventual formalization of Wheeler graphs [Gagie et al., 2017]. Along the way, we will define and update our notions of what it means to track a consecutive range of elements in the structure, and what it means for an index to be efficient. We will also connect these notions to automata [Sipser, 1996], noting how the indexability of Wheeler graphs (also called Wheeler automata) is connected to the mechanics of how to efficiently represent and simulate a finite automaton [Alanko et al., 2021]. With this context, we can imagine improved indexes for the future of genomics and pangenomics. De Bruijn are extremely practical and are the most widely used among the non-string data structures that are also Wheeler graphs. But we might prefer other options. For example, de Bruijn graphs have the undesirable property that they usually encode not only the true longer-than-k substrings of the original text, but also "false" substrings that span repeats. Related to this, paths through the de Bruijn graph can "glue" substrings together that are horizontally distant in the MSA. Could other Wheeler graphs be practical alternatives to de Bruijn graphs? For instance, the original GCSA study by Sirén, Välimäki and Mäkinen proposed a way to convert a multiple alignment into an automaton that either is a Wheeler graph or can be made into one [Sirén et al., 2014]. This warrants further exploration, possibly with the help of improved tools for solving the NP-complete problem of recognizing whether a graph is a Wheeler graph [Chao et al., 2023]. The notion of BWT tunnels [Baier, 2018] gives another route: we can begin with a concatenated pangenome strings and compress it by identifying and collapsing BWT tunnels. This yields a Wheeler graph that is compressed like the de Bruijn graph, but without departing from the exact contents or coordinate systems of the original genomes. The future might need us to explore all these Wheeler-graph indexes, along with the also highly practical and always-improving world of indexes buiover collections of strings [Gagie et al., 2018].

Cite as

Ben Langmead. We Are What We Index; a Primer for the Wheeler Graph Era (Invited Talk). In 25th International Conference on Algorithms for Bioinformatics (WABI 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 344, pp. 2:1-2:2, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{langmead:LIPIcs.WABI.2025.2,
  author =	{Langmead, Ben},
  title =	{{We Are What We Index; a Primer for the Wheeler Graph Era}},
  booktitle =	{25th International Conference on Algorithms for Bioinformatics (WABI 2025)},
  pages =	{2:1--2:2},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-386-7},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{344},
  editor =	{Brejov\'{a}, Bro\v{n}a and Patro, Rob},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2025.2},
  URN =		{urn:nbn:de:0030-drops-239288},
  doi =		{10.4230/LIPIcs.WABI.2025.2},
  annote =	{Keywords: Indexing, Burrows-Wheeler Transform}
}
Document
A Survey of the Bijective Burrows-Wheeler Transform

Authors: Hideo Bannai, Dominik Köppl, and Zsuzsanna Lipták

Published in: OASIcs, Volume 131, The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday (2025)


Abstract
The Bijective BWT (BBWT), conceived by Scott in 2007, later summarized in a preprint by Gil and Scott in 2009 (arXiv 2012), is a variant of the Burrows-Wheeler Transform which is bijective: every string is the BBWT of some string. Indeed, the BBWT of a string is the extended BWT [Mantaci et al., 2007] of the factors of its Lyndon factorization. The BBWT has been receiving increasing interest in recent years. In this paper, we survey existing research on the BBWT, starting with its history and motivation. We then present algorithmic topics including construction algorithms with various complexities and an index on top of the BBWT for pattern matching. We subsequently address some properties of the BBWT as a compressor, discussing robustness to operations such as reversal, edits, rotation, as well as compression power. We close with listing other bijective variants of the BWT and open problems concerning the BBWT.

Cite as

Hideo Bannai, Dominik Köppl, and Zsuzsanna Lipták. A Survey of the Bijective Burrows-Wheeler Transform. In The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 131, pp. 2:1-2:26, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{bannai_et_al:OASIcs.Manzini.2,
  author =	{Bannai, Hideo and K\"{o}ppl, Dominik and Lipt\'{a}k, Zsuzsanna},
  title =	{{A Survey of the Bijective Burrows-Wheeler Transform}},
  booktitle =	{The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday},
  pages =	{2:1--2:26},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-390-4},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{131},
  editor =	{Ferragina, Paolo and Gagie, Travis and Navarro, Gonzalo},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Manzini.2},
  URN =		{urn:nbn:de:0030-drops-239100},
  doi =		{10.4230/OASIcs.Manzini.2},
  annote =	{Keywords: Burrows-Wheeler Transform, compression, text indexing, repetitiveness measure, Lyndon words, index construction algorithms, bijective string transformation}
}
Document
Circular Dictionary Matching Using Extended BWT

Authors: Wing-Kai Hon, Rahul Shah, and Sharma V. Thankachan

Published in: OASIcs, Volume 131, The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday (2025)


Abstract
The dictionary matching problem involves preprocessing a set of strings (patterns) into a data structure that efficiently identifies all occurrences of these patterns within a query string (text). In this work, we investigate a variation of this problem, termed circular dictionary matching, where the patterns are circular, meaning their cyclic shifts are also considered valid patterns. Such patterns naturally occur in areas such as bioinformatics and computational geometry. Based on the extended Burrows-Wheeler Transformation (eBWT), we design a space-efficient solution for this problem. Specifically, we show that a dictionary of d circular patterns of total length n can be indexed in nlog σ + O(n+dlog n+σ log n) bits of space and support circular dictionary matching on a query text T in O((|T|+occ)log n) time, where σ represents the size of the underlying alphabet and occ represents the output size.

Cite as

Wing-Kai Hon, Rahul Shah, and Sharma V. Thankachan. Circular Dictionary Matching Using Extended BWT. In The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 131, pp. 11:1-11:14, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{hon_et_al:OASIcs.Manzini.11,
  author =	{Hon, Wing-Kai and Shah, Rahul and Thankachan, Sharma V.},
  title =	{{Circular Dictionary Matching Using Extended BWT}},
  booktitle =	{The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday},
  pages =	{11:1--11:14},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-390-4},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{131},
  editor =	{Ferragina, Paolo and Gagie, Travis and Navarro, Gonzalo},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Manzini.11},
  URN =		{urn:nbn:de:0030-drops-239195},
  doi =		{10.4230/OASIcs.Manzini.11},
  annote =	{Keywords: String algorithms, Burrows-Wheeler transformation, suffix trees, succinct data structures}
}
Document
Wheeler Graphs and Wheeler Languages

Authors: Nicola Cotumaccio, Giovanna D'Agostino, Daniel Gibney, Alberto Policriti, Nicola Prezza, and Sharma V. Thankachan

Published in: OASIcs, Volume 131, The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday (2025)


Abstract
Suffix sorting stands at the core of the most efficient solutions for indexed pattern matching: the suffix tree, the suffix array, compressed indexes based on the Burrows-Wheeler transform, and so on. In [Gagie, Manzini, Sirén, TCS 2017] this concept was extended to labeled graphs, obtaining the rich class of Wheeler graphs. This work opened a very fruitful line of research, ultimately generating results able to bridge the fields of compressed data structures, graph theory, and regular language theory. In a Wheeler graph, nodes are sorted according to the alphabetic order of their incoming labels, propagating this order through pairs of equally-labeled edges. This apparently-simple definition makes it possible to solve on Wheeler graphs problems (including, but not limited to: compression, subpath queries, NFA equivalence, determinization, minimization) that on general labeled graphs are extremely hard to solve, and induces a rich structure in the class of regular languages (Wheeler languages) recognized by automata whose state transition is a Wheeler graph. The goal of this survey is to provide a summary of (and intuitions behind) the results on Wheeler graphs that appeared in the literature since their introduction, in addition to a discussion of interesting problems that are still open in the field.

Cite as

Nicola Cotumaccio, Giovanna D'Agostino, Daniel Gibney, Alberto Policriti, Nicola Prezza, and Sharma V. Thankachan. Wheeler Graphs and Wheeler Languages. In The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 131, pp. 12:1-12:28, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{cotumaccio_et_al:OASIcs.Manzini.12,
  author =	{Cotumaccio, Nicola and D'Agostino, Giovanna and Gibney, Daniel and Policriti, Alberto and Prezza, Nicola and Thankachan, Sharma V.},
  title =	{{Wheeler Graphs and Wheeler Languages}},
  booktitle =	{The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday},
  pages =	{12:1--12:28},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-390-4},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{131},
  editor =	{Ferragina, Paolo and Gagie, Travis and Navarro, Gonzalo},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Manzini.12},
  URN =		{urn:nbn:de:0030-drops-239205},
  doi =		{10.4230/OASIcs.Manzini.12},
  annote =	{Keywords: Wheeler languages, Wheeler graphs, pattern matching, indexing, compressed data structures}
}
Document
Graph Indexing Beyond Wheeler Graphs

Authors: Jarno N. Alanko, Elena Biagi, Massimo Equi, Veli Mäkinen, Simon J. Puglisi, Nicola Rizzo, Kunihiko Sadakane, and Jouni Sirén

Published in: OASIcs, Volume 131, The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday (2025)


Abstract
After the discovery of the FM index, which linked the Burrows-Wheeler transform (BWT) to pattern matching on strings, several contemporaneous strands of research began on indexing more complex structures with the BWT, such as tries, finite languages, de Bruijn graphs, and aligned sequences. These directions can now be viewed as culminating in the theory of Wheeler Graphs, but sometimes they go beyond. This chapter reviews the significant body of "proto Wheeler Graph" indexes, many of which exploit characteristics of their specific case to outperform Wheeler graphs, especially in practice.

Cite as

Jarno N. Alanko, Elena Biagi, Massimo Equi, Veli Mäkinen, Simon J. Puglisi, Nicola Rizzo, Kunihiko Sadakane, and Jouni Sirén. Graph Indexing Beyond Wheeler Graphs. In The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 131, pp. 13:1-13:29, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{alanko_et_al:OASIcs.Manzini.13,
  author =	{Alanko, Jarno N. and Biagi, Elena and Equi, Massimo and M\"{a}kinen, Veli and Puglisi, Simon J. and Rizzo, Nicola and Sadakane, Kunihiko and Sir\'{e}n, Jouni},
  title =	{{Graph Indexing Beyond Wheeler Graphs}},
  booktitle =	{The Expanding World of Compressed Data: A Festschrift for Giovanni Manzini's 60th Birthday},
  pages =	{13:1--13:29},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-390-4},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{131},
  editor =	{Ferragina, Paolo and Gagie, Travis and Navarro, Gonzalo},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Manzini.13},
  URN =		{urn:nbn:de:0030-drops-239215},
  doi =		{10.4230/OASIcs.Manzini.13},
  annote =	{Keywords: indexing, compression, compressed data structures, string algorithms, pattern matching}
}
Document
On the Impact of Provenance Semiring Theory on the Design of a Provenance-Aware Database System

Authors: Pierre Senellart

Published in: OASIcs, Volume 119, The Provenance of Elegance in Computation - Essays Dedicated to Val Tannen (2024)


Abstract
We report on the impact that the theory of provenance semirings, developed by Val Tannen and his collaborators, has had on the design on a practical system for maintaining the provenance of query results over a relational database, namely ProvSQL.

Cite as

Pierre Senellart. On the Impact of Provenance Semiring Theory on the Design of a Provenance-Aware Database System. In The Provenance of Elegance in Computation - Essays Dedicated to Val Tannen. Open Access Series in Informatics (OASIcs), Volume 119, pp. 9:1-9:10, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2024)


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@InProceedings{senellart:OASIcs.Tannen.9,
  author =	{Senellart, Pierre},
  title =	{{On the Impact of Provenance Semiring Theory on the Design of a Provenance-Aware Database System}},
  booktitle =	{The Provenance of Elegance in Computation - Essays Dedicated to Val Tannen},
  pages =	{9:1--9:10},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-320-1},
  ISSN =	{2190-6807},
  year =	{2024},
  volume =	{119},
  editor =	{Amarilli, Antoine and Deutsch, Alin},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Tannen.9},
  URN =		{urn:nbn:de:0030-drops-201050},
  doi =		{10.4230/OASIcs.Tannen.9},
  annote =	{Keywords: provenance, provenance semiring, ProvSQL}
}
Document
Prefix-Free Parsing for Building Large Tunnelled Wheeler Graphs

Authors: Adrián Goga and Andrej Baláž

Published in: LIPIcs, Volume 242, 22nd International Workshop on Algorithms in Bioinformatics (WABI 2022)


Abstract
We propose a new technique for creating a space-efficient index for large repetitive text collections, such as pangenomic databases containing sequences of many individuals from the same species. We combine two recent techniques from this area: Wheeler graphs (Gagie et al., 2017) and prefix-free parsing (PFP, Boucher et al., 2019). Wheeler graphs are a general framework encompassing several indexes based on the Burrows-Wheeler transform (BWT), such as the FM-index. Wheeler graphs admit a succinct representation which can be further compacted by employing the idea of tunnelling, which exploits redundancies in the form of parallel, equally-labelled paths called blocks that can be merged into a single path. The problem of finding the optimal set of blocks for tunnelling, i.e. the one that minimizes the size of the resulting Wheeler graph, is known to be NP-complete and remains the most computationally challenging part of the tunnelling process. To find an adequate set of blocks in less time, we propose a new method based on the prefix-free parsing (PFP). The idea of PFP is to divide the input text into phrases of roughly equal sizes that overlap by a fixed number of characters. The phrases are then sorted lexicographically. The original text is represented by a sequence of phrase ranks (the parse) and a list of all used phrases (the dictionary). In repetitive texts, the PFP representation of the text is generally much shorter than the original since individual phrases are used many times in the parse, thus reducing the size of the dictionary. To speed up the block selection for tunnelling, we apply the PFP to obtain the parse and the dictionary of the original text, tunnel the Wheeler graph of the parse using existing heuristics and subsequently use this tunnelled parse to construct a compact Wheeler graph of the original text. Compared with constructing a Wheeler graph from the original text without PFP, our method is much faster and uses less memory on collections of pangenomic sequences. Therefore, our method enables the use of Wheeler graphs as a pangenomic reference for real-world pangenomic datasets.

Cite as

Adrián Goga and Andrej Baláž. Prefix-Free Parsing for Building Large Tunnelled Wheeler Graphs. In 22nd International Workshop on Algorithms in Bioinformatics (WABI 2022). Leibniz International Proceedings in Informatics (LIPIcs), Volume 242, pp. 18:1-18:12, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2022)


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@InProceedings{goga_et_al:LIPIcs.WABI.2022.18,
  author =	{Goga, Adri\'{a}n and Bal\'{a}\v{z}, Andrej},
  title =	{{Prefix-Free Parsing for Building Large Tunnelled Wheeler Graphs}},
  booktitle =	{22nd International Workshop on Algorithms in Bioinformatics (WABI 2022)},
  pages =	{18:1--18:12},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-243-3},
  ISSN =	{1868-8969},
  year =	{2022},
  volume =	{242},
  editor =	{Boucher, Christina and Rahmann, Sven},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2022.18},
  URN =		{urn:nbn:de:0030-drops-170529},
  doi =		{10.4230/LIPIcs.WABI.2022.18},
  annote =	{Keywords: Wheeler graphs, BWT tunnelling, prefix-free parsing, pangenomic graphs}
}
Document
Compressing and Indexing Aligned Readsets

Authors: Travis Gagie, Garance Gourdel, and Giovanni Manzini

Published in: LIPIcs, Volume 201, 21st International Workshop on Algorithms in Bioinformatics (WABI 2021)


Abstract
Compressed full-text indexes are one of the main success stories of bioinformatics data structures but even they struggle to handle some DNA readsets. This may seem surprising since, at least when dealing with short reads from the same individual, the readset will be highly repetitive and, thus, highly compressible. If we are not careful, however, this advantage can be more than offset by two disadvantages: first, since most base pairs are included in at least tens reads each, the uncompressed readset is likely to be at least an order of magnitude larger than the individual’s uncompressed genome; second, these indexes usually pay some space overhead for each string they store, and the total overhead can be substantial when dealing with millions of reads. The most successful compressed full-text indexes for readsets so far are based on the Extended Burrows-Wheeler Transform (EBWT) and use a sorting heuristic to try to reduce the space overhead per read, but they still treat the reads as separate strings and thus may not take full advantage of the readset’s structure. For example, if we have already assembled an individual’s genome from the readset, then we can usually use it to compress the readset well: e.g., we store the gap-coded list of reads' starting positions; we store the list of their lengths, which is often highly compressible; and we store information about the sequencing errors, which are rare with short reads. There is nowhere, however, where we can plug an assembled genome into the EBWT. In this paper we show how to use one or more assembled or partially assembled genome as the basis for a compressed full-text index of its readset. Specifically, we build a labelled tree by taking the assembled genome as a trunk and grafting onto it the reads that align to it, at the starting positions of their alignments. Next, we compute the eXtended Burrows-Wheeler Transform (XBWT) of the resulting labelled tree and build a compressed full-text index on that. Although this index can occasionally return false positives, it is usually much more compact than the alternatives. Following the established practice for datasets with many repetitions, we compare different full-text indices by looking at the number of runs in the transformed strings. For a human Chr19 readset our preliminary experiments show that eliminating separators characters from the EBWT reduces the number of runs by 19%, from 220 million to 178 million, and using the XBWT reduces it by a further 15%, to 150 million.

Cite as

Travis Gagie, Garance Gourdel, and Giovanni Manzini. Compressing and Indexing Aligned Readsets. In 21st International Workshop on Algorithms in Bioinformatics (WABI 2021). Leibniz International Proceedings in Informatics (LIPIcs), Volume 201, pp. 13:1-13:21, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2021)


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@InProceedings{gagie_et_al:LIPIcs.WABI.2021.13,
  author =	{Gagie, Travis and Gourdel, Garance and Manzini, Giovanni},
  title =	{{Compressing and Indexing Aligned Readsets}},
  booktitle =	{21st International Workshop on Algorithms in Bioinformatics (WABI 2021)},
  pages =	{13:1--13:21},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-200-6},
  ISSN =	{1868-8969},
  year =	{2021},
  volume =	{201},
  editor =	{Carbone, Alessandra and El-Kebir, Mohammed},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.WABI.2021.13},
  URN =		{urn:nbn:de:0030-drops-143660},
  doi =		{10.4230/LIPIcs.WABI.2021.13},
  annote =	{Keywords: data compression, compact data structures, FM-index, Burrows-Wheeler Transform, EBWT, XBWT, DNA reads}
}
Document
On Undetected Redundancy in the Burrows-Wheeler Transform

Authors: Uwe Baier

Published in: LIPIcs, Volume 105, 29th Annual Symposium on Combinatorial Pattern Matching (CPM 2018)


Abstract
The Burrows-Wheeler-Transform (BWT) is an invertible permutation of a text known to be highly compressible but also useful for sequence analysis, what makes the BWT highly attractive for lossless data compression. In this paper, we present a new technique to reduce the size of a BWT using its combinatorial properties, while keeping it invertible. The technique can be applied to any BWT-based compressor, and, as experiments show, is able to reduce the encoding size by 8-16 % on average and up to 33-57 % in the best cases (depending on the BWT-compressor used), making BWT-based compressors competitive or even superior to today's best lossless compressors.

Cite as

Uwe Baier. On Undetected Redundancy in the Burrows-Wheeler Transform. In 29th Annual Symposium on Combinatorial Pattern Matching (CPM 2018). Leibniz International Proceedings in Informatics (LIPIcs), Volume 105, pp. 3:1-3:15, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2018)


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@InProceedings{baier:LIPIcs.CPM.2018.3,
  author =	{Baier, Uwe},
  title =	{{On Undetected Redundancy in the Burrows-Wheeler Transform}},
  booktitle =	{29th Annual Symposium on Combinatorial Pattern Matching (CPM 2018)},
  pages =	{3:1--3:15},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-074-3},
  ISSN =	{1868-8969},
  year =	{2018},
  volume =	{105},
  editor =	{Navarro, Gonzalo and Sankoff, David and Zhu, Binhai},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2018.3},
  URN =		{urn:nbn:de:0030-drops-87049},
  doi =		{10.4230/LIPIcs.CPM.2018.3},
  annote =	{Keywords: Lossless data compression, BWT, Tunneling}
}
Document
Linear-time Suffix Sorting - A New Approach for Suffix Array Construction

Authors: Uwe Baier

Published in: LIPIcs, Volume 54, 27th Annual Symposium on Combinatorial Pattern Matching (CPM 2016)


Abstract
This paper presents a new approach for linear-time suffix sorting. It introduces a new sorting principle that can be used to build the first non-recursive linear-time suffix array construction algorithm named GSACA. Although GSACA cannot keep up with the performance of state of the art suffix array construction algorithms, the algorithm introduces a couple of new ideas for suffix array construction, and therefore can be seen as an ’idea collection’ for further suffix array construction improvements.

Cite as

Uwe Baier. Linear-time Suffix Sorting - A New Approach for Suffix Array Construction. In 27th Annual Symposium on Combinatorial Pattern Matching (CPM 2016). Leibniz International Proceedings in Informatics (LIPIcs), Volume 54, pp. 23:1-23:12, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2016)


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@InProceedings{baier:LIPIcs.CPM.2016.23,
  author =	{Baier, Uwe},
  title =	{{Linear-time Suffix Sorting - A New Approach for Suffix Array Construction}},
  booktitle =	{27th Annual Symposium on Combinatorial Pattern Matching (CPM 2016)},
  pages =	{23:1--23:12},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-012-5},
  ISSN =	{1868-8969},
  year =	{2016},
  volume =	{54},
  editor =	{Grossi, Roberto and Lewenstein, Moshe},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2016.23},
  URN =		{urn:nbn:de:0030-drops-60698},
  doi =		{10.4230/LIPIcs.CPM.2016.23},
  annote =	{Keywords: Suffix array, sorting algorithm, linear time}
}
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