19 Search Results for "Loukides, Grigorios"


Document
Time-Optimal Construction of String Synchronizing Sets

Authors: Jonas Ellert and Tomasz Kociumaka

Published in: LIPIcs, Volume 364, 43rd International Symposium on Theoretical Aspects of Computer Science (STACS 2026)


Abstract
A powerful design principle behind many modern string algorithms is local consistency: breaking the symmetry between string positions based on their small contexts so that matching fragments are handled consistently. Among the most influential instantiations of this principle are string synchronizing sets [Kempa & Kociumaka; STOC 2019]. A τ-synchronizing set of a string of length n is a set of O(n/τ) string positions, chosen using their length-2τ contexts, such that (outside of highly periodic regions) every block of τ consecutive positions contains at least one element of the set. Synchronizing sets have found dozens of applications in diverse settings, from quantum and dynamic algorithms to fully compressed computation. In the classic word RAM model, particularly for strings over small alphabets, they enabled faster solutions to core problems in data compression, text indexing, and string similarity. In this work, we show that any string T ∈ [0 .. σ)ⁿ can be preprocessed in O(n log σ / log n) time so that, for any given integer τ ∈ [1 .. n], a τ-synchronizing set of T can be constructed in O((n log τ)/(τ log n)) time. Both bounds are optimal in the word RAM model with machine word size w = Θ(log n), matching the information-theoretic minimum for the input and output sizes, respectively. Previously, constructing a τ-synchronizing set required O(n/τ) time after an O(n)-time preprocessing [Kociumaka, Radoszewski, Rytter, and Waleń; SICOMP 2024], or, in the restricted regime of τ < 0.2 log_σ n, without any preprocessing needed [Kempa & Kociumaka; STOC 2019]. A simple instantiation of our method outputs the synchronizing set as a sorted list in O(n/τ) time, or as a bitmask in O(n/log n) time. Our optimal construction produces a compact fully indexable dictionary, supporting select queries in O(1) time and rank queries in O(log ((log τ)/(log log n))) time. The latter complexity matches known unconditional cell-probe lower bounds for τ ≤ n^{1-Ω(1)}. To achieve this, we introduce a general framework for efficiently processing sparse integer sequences via a custom variable-length encoding. We also augment the optimal variant of van Emde Boas trees [Pătraşcu & Thorup; STOC 2006] with a deterministic linear-time construction. When the set is represented as a bitmask under our sparse encoding, the same guarantees for select and rank queries hold after preprocessing in time proportional to the size of our encoding (in words).

Cite as

Jonas Ellert and Tomasz Kociumaka. Time-Optimal Construction of String Synchronizing Sets. In 43rd International Symposium on Theoretical Aspects of Computer Science (STACS 2026). Leibniz International Proceedings in Informatics (LIPIcs), Volume 364, pp. 36:1-36:22, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2026)


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@InProceedings{ellert_et_al:LIPIcs.STACS.2026.36,
  author =	{Ellert, Jonas and Kociumaka, Tomasz},
  title =	{{Time-Optimal Construction of String Synchronizing Sets}},
  booktitle =	{43rd International Symposium on Theoretical Aspects of Computer Science (STACS 2026)},
  pages =	{36:1--36:22},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-412-3},
  ISSN =	{1868-8969},
  year =	{2026},
  volume =	{364},
  editor =	{Mahajan, Meena and Manea, Florin and McIver, Annabelle and Thắng, Nguy\~{ê}n Kim},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.STACS.2026.36},
  URN =		{urn:nbn:de:0030-drops-255258},
  doi =		{10.4230/LIPIcs.STACS.2026.36},
  annote =	{Keywords: synchronizing sets, local consistency, packed strings}
}
Document
Better Indexing for Rectangular Pattern Matching

Authors: Paweł Gawrychowski and Adam Górkiewicz

Published in: LIPIcs, Volume 351, 33rd Annual European Symposium on Algorithms (ESA 2025)


Abstract
We revisit the complexity of building, given a two-dimensional string of size n, an indexing structure that allows locating all k occurrences of a two-dimensional pattern of size m. While a structure of size 𝒪(n) with query time 𝒪(m+k) is known for this problem under the additional assumption that the pattern is a square [Giancarlo, SICOMP 1995], a popular belief was that for rectangular patterns one cannot achieve such (or even similar) bounds, due to a lower bound for a certain natural class of approaches [Giancarlo, WADS 1993]. We show that, in fact, it is possible to construct a very simple structure of size 𝒪(nlog n) that supports such queries for any rectangular pattern in 𝒪(m+klog^{ε}n) time, for any ε > 0.

Cite as

Paweł Gawrychowski and Adam Górkiewicz. Better Indexing for Rectangular Pattern Matching. In 33rd Annual European Symposium on Algorithms (ESA 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 351, pp. 33:1-33:7, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{gawrychowski_et_al:LIPIcs.ESA.2025.33,
  author =	{Gawrychowski, Pawe{\l} and G\'{o}rkiewicz, Adam},
  title =	{{Better Indexing for Rectangular Pattern Matching}},
  booktitle =	{33rd Annual European Symposium on Algorithms (ESA 2025)},
  pages =	{33:1--33:7},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-395-9},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{351},
  editor =	{Benoit, Anne and Kaplan, Haim and Wild, Sebastian and Herman, Grzegorz},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.ESA.2025.33},
  URN =		{urn:nbn:de:0030-drops-245011},
  doi =		{10.4230/LIPIcs.ESA.2025.33},
  annote =	{Keywords: 2D strings, pattern matching, string indexing}
}
Document
Research
Specific Patterns Against Reference Sequences

Authors: Marie-Pierre Béal and Maxime Crochemore

Published in: OASIcs, Volume 132, From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday (2025)


Abstract
We design alignment-free techniques for comparing a set of sequences or just a word, called a target, against another set of words, called a reference. This is done with the detection of factor patterns that distinguish the target from the reference. A target-specific factor of a target T against a reference R is then a factor w of a word in T that is not a factor of a word in R but whose proper factors of w are factors of a word in R. The strategy is based on the notion of minimal absent/forbidden words. We first address the computation of the set of target-specific factors of a target T against a reference R, where T and R are finite sets of sequences. The result is the construction of an automaton accepting the set of all considered target-specific factors. The construction algorithm runs in linear time according to the size of T ∪ R. The second result is the design of an algorithm to compute all the occurrences in a single sequence T of its target-specific factors against a reference R. The algorithm runs in real-time on the target sequence, independently of the number of occurrences of target-specific factors.

Cite as

Marie-Pierre Béal and Maxime Crochemore. Specific Patterns Against Reference Sequences. In From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 132, pp. 14:1-14:12, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{beal_et_al:OASIcs.Grossi.14,
  author =	{B\'{e}al, Marie-Pierre and Crochemore, Maxime},
  title =	{{Specific Patterns Against Reference Sequences}},
  booktitle =	{From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday},
  pages =	{14:1--14:12},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-391-1},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{132},
  editor =	{Conte, Alessio and Marino, Andrea and Rosone, Giovanna and Vitter, Jeffrey Scott},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Grossi.14},
  URN =		{urn:nbn:de:0030-drops-238130},
  doi =		{10.4230/OASIcs.Grossi.14},
  annote =	{Keywords: Specific pattern, Minimal absent word, Minimal forbidden word, Directed Acyclic Word Graph (DAWG), Suffix automaton}
}
Document
Research
Faster Run-Length Compressed Suffix Arrays

Authors: Nathaniel K. Brown, Travis Gagie, Giovanni Manzini, Gonzalo Navarro, and Marinella Sciortino

Published in: OASIcs, Volume 132, From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday (2025)


Abstract
We first review how we can store a run-length compressed suffix array (RLCSA) for a text T of length n over an alphabet of size σ whose Burrows-Wheeler Transform (BWT) consists of r runs in O (r log (n / r) + r log σ + σ) bits such that later, given character a and the suffix-array (SA) interval for P, we can find the SA interval for a P in O (log r_a + log log n) time, where r_a is the number of runs of copies of a in the BWT. We then show how to modify the RLCSA such that we find the SA interval for a P in only O (log r_a) time, without increasing its asymptotic space bound. Our key idea is applying a result by Nishimoto and Tabei (ICALP 2021) and then replacing rank queries on sparse bitvectors by a constant number of select queries. We also review two-level indexing and discuss how our faster RLCSA may be useful in improving it. Finally, we briefly discuss how two-level indexing may speed up a recent heuristic for finding maximal exact matches of a pattern with respect to an indexed text.

Cite as

Nathaniel K. Brown, Travis Gagie, Giovanni Manzini, Gonzalo Navarro, and Marinella Sciortino. Faster Run-Length Compressed Suffix Arrays. In From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 132, pp. 10:1-10:15, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{brown_et_al:OASIcs.Grossi.10,
  author =	{Brown, Nathaniel K. and Gagie, Travis and Manzini, Giovanni and Navarro, Gonzalo and Sciortino, Marinella},
  title =	{{Faster Run-Length Compressed Suffix Arrays}},
  booktitle =	{From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday},
  pages =	{10:1--10:15},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-391-1},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{132},
  editor =	{Conte, Alessio and Marino, Andrea and Rosone, Giovanna and Vitter, Jeffrey Scott},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Grossi.10},
  URN =		{urn:nbn:de:0030-drops-238095},
  doi =		{10.4230/OASIcs.Grossi.10},
  annote =	{Keywords: Run-length compressed suffix arrays, interpolative coding, two-level indexing}
}
Document
Research
On String and Graph Sanitization

Authors: Giulia Bernardini, Huiping Chen, Grigorios Loukides, and Solon P. Pissis

Published in: OASIcs, Volume 132, From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday (2025)


Abstract
Data sanitization is a process that conceals sensitive patterns from a given dataset. A secondary goal is to not severely harm the utility of the underlying data along this process. We survey some recent advancements on two related data sanitization topics: string and graph sanitization. In particular, we highlight the important contributions of our friend Prof. Roberto Grossi along this journey.

Cite as

Giulia Bernardini, Huiping Chen, Grigorios Loukides, and Solon P. Pissis. On String and Graph Sanitization. In From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 132, pp. 9:1-9:10, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{bernardini_et_al:OASIcs.Grossi.9,
  author =	{Bernardini, Giulia and Chen, Huiping and Loukides, Grigorios and Pissis, Solon P.},
  title =	{{On String and Graph Sanitization}},
  booktitle =	{From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday},
  pages =	{9:1--9:10},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-391-1},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{132},
  editor =	{Conte, Alessio and Marino, Andrea and Rosone, Giovanna and Vitter, Jeffrey Scott},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Grossi.9},
  URN =		{urn:nbn:de:0030-drops-238086},
  doi =		{10.4230/OASIcs.Grossi.9},
  annote =	{Keywords: data privacy, data sanitization, string algorithms, graph algorithms}
}
Document
Research
Designing Output Sensitive Algorithms for Subgraph Enumeration

Authors: Alessio Conte, Kazuhiro Kurita, Andrea Marino, Giulia Punzi, Takeaki Uno, and Kunihiro Wasa

Published in: OASIcs, Volume 132, From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday (2025)


Abstract
The enumeration of all subgraphs respecting some structural property is a fundamental task in theoretical computer science, with practical applications in many branches of data mining and network analysis. It is often of interest to only consider solutions (subgraphs) that are maximal under inclusion, and to achieve output-sensitive complexity, i.e., bounding the running time with respect to the number of subgraphs produced. In this paper, we provide a survey of techniques for designing output-sensitive algorithms for subgraph enumeration, including partition-based approaches such as flashlight search, solution-graph traversal methods such as reverse search, and cost amortization strategies such as push-out amortization. We also briefly discuss classes of efficiency, hardness of enumeration, and variants such as approximate enumeration. The paper is meant as an accessible handbook for learning the basics of the field and as a practical reference for selecting state-of-the-art subgraph enumeration strategies fitting to one’s needs.

Cite as

Alessio Conte, Kazuhiro Kurita, Andrea Marino, Giulia Punzi, Takeaki Uno, and Kunihiro Wasa. Designing Output Sensitive Algorithms for Subgraph Enumeration. In From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday. Open Access Series in Informatics (OASIcs), Volume 132, pp. 19:1-19:40, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{conte_et_al:OASIcs.Grossi.19,
  author =	{Conte, Alessio and Kurita, Kazuhiro and Marino, Andrea and Punzi, Giulia and Uno, Takeaki and Wasa, Kunihiro},
  title =	{{Designing Output Sensitive Algorithms for Subgraph Enumeration}},
  booktitle =	{From Strings to Graphs, and Back Again: A Festschrift for Roberto Grossi's 60th Birthday},
  pages =	{19:1--19:40},
  series =	{Open Access Series in Informatics (OASIcs)},
  ISBN =	{978-3-95977-391-1},
  ISSN =	{2190-6807},
  year =	{2025},
  volume =	{132},
  editor =	{Conte, Alessio and Marino, Andrea and Rosone, Giovanna and Vitter, Jeffrey Scott},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/OASIcs.Grossi.19},
  URN =		{urn:nbn:de:0030-drops-238180},
  doi =		{10.4230/OASIcs.Grossi.19},
  annote =	{Keywords: Graph algorithms, Graph enumeration, Output sensitive enumeration}
}
Document
U-Index: A Universal Indexing Framework for Matching Long Patterns

Authors: Lorraine A. K. Ayad, Gabriele Fici, Ragnar Groot Koerkamp, Grigorios Loukides, Rob Patro, Giulio Ermanno Pibiri, and Solon P. Pissis

Published in: LIPIcs, Volume 338, 23rd International Symposium on Experimental Algorithms (SEA 2025)


Abstract
Motivation. Text indexing is a fundamental and well-studied problem. Classic solutions to this problem either replace the original text with a compressed representation, e.g., the FM-index and its variants, or keep it uncompressed but attach some redundancy - an index - to accelerate matching, e.g., the suffix array. The former solutions thus retain excellent compressed space, but are practically slow to construct and query. The latter approaches, instead, sacrifice space efficiency but are typically faster; for example, the suffix array takes much more space than the text itself for commonly used alphabets, like ASCII or DNA, but it is very fast to construct and query. Methods. In this paper, we show that efficient text indexing can be achieved using just a small extra space on top of the original text, provided that the query patterns are sufficiently long. More specifically, we develop a new indexing paradigm in which a sketch of a query pattern is first matched against a sketch of the text. Once candidate matches are retrieved, they are verified using the original text. This paradigm is thus universal in the sense that it allows us to use any solution to index the sketched text, like a suffix array, FM-index, or r-index. Results. We explore both the theory and the practice of this universal framework. With an extensive experimental analysis, we show that, surprisingly, universal indexes can be constructed much faster than their unsketched counterparts and take a fraction of the space, as a direct consequence of (i) having a lower bound on the length of patterns and (ii) working in sketch space. Furthermore, these data structures have the potential of retaining or even improving query time, because matching against the sketched text is faster and verifying candidates can be theoretically done in constant time per occurrence (or, in practice, by short and cache-friendly scans of the text). Finally, we discuss some important applications of this novel indexing paradigm to computational biology. We hypothesize that such indexes will be particularly effective when the queries are sufficiently long, and so we demonstrate applications in long-read mapping.

Cite as

Lorraine A. K. Ayad, Gabriele Fici, Ragnar Groot Koerkamp, Grigorios Loukides, Rob Patro, Giulio Ermanno Pibiri, and Solon P. Pissis. U-Index: A Universal Indexing Framework for Matching Long Patterns. In 23rd International Symposium on Experimental Algorithms (SEA 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 338, pp. 4:1-4:18, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{ayad_et_al:LIPIcs.SEA.2025.4,
  author =	{Ayad, Lorraine A. K. and Fici, Gabriele and Groot Koerkamp, Ragnar and Loukides, Grigorios and Patro, Rob and Pibiri, Giulio Ermanno and Pissis, Solon P.},
  title =	{{U-Index: A Universal Indexing Framework for Matching Long Patterns}},
  booktitle =	{23rd International Symposium on Experimental Algorithms (SEA 2025)},
  pages =	{4:1--4:18},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-375-1},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{338},
  editor =	{Mutzel, Petra and Prezza, Nicola},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.SEA.2025.4},
  URN =		{urn:nbn:de:0030-drops-232420},
  doi =		{10.4230/LIPIcs.SEA.2025.4},
  annote =	{Keywords: Text Indexing, Sketching, Minimizers, Hashing}
}
Document
Faster Approximate Elastic-Degenerate String Matching - Part A

Authors: Solon P. Pissis, Jakub Radoszewski, and Wiktor Zuba

Published in: LIPIcs, Volume 331, 36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025)


Abstract
An elastic-degenerate (ED) string 𝐓 is a sequence 𝐓 = 𝐓[1] ⋯ 𝐓[n] of n finite sets of strings. The cardinality m of 𝐓 is the total number of strings in 𝐓[i], for all i ∈ [1..n]. The size N of 𝐓 is the total length of all m strings of 𝐓. ED strings have been introduced to represent a set of closely-related DNA sequences. Let P = P[1..p] be a pattern of length p and k > 0 be an integer. We consider the problem of k-Approximate ED String Matching (EDSM): searching k-approximate occurrences of P in the language of 𝐓. We call k-Approximate EDSM under the Hamming distance, k-Mismatch EDSM; and we call k-Approximate EDSM under edit distance, k-Edit EDSM. Bernardini et al. (Theoretical Computer Science, 2020) showed a simple 𝒪(k m p + kN)-time algorithm for k-Mismatch EDSM and an 𝒪(k² m p + kN)-time algorithm for k-Edit EDSM. We improve the dependency on k in both results, obtaining an Õ(k^{2/3}mp+√kN)-time algorithm for k-Mismatch EDSM and an Õ(kmp+ kN)-time algorithm for k-Edit EDSM. Bernardini et al. (Theory of Computing Systems, 2024) presented several algorithms for 1-Approximate EDSM working in Õ(np²+N) time. They have also left the possibility to generalize these solutions for k > 1 as an open problem. We improve the runtime of their solution for 1-Mismatch and 1-Edit EDSM from Õ(np²+N) to 𝒪(np²+N). We further show algorithms for k-Approximate EDSM for the Hamming and edit distances working in Õ(np² + N) time, for any constant k > 0. Finally, we show how our techniques can be applied to improve upon the complexity of the k-Approximate ED String Intersection and k-Approximate Doubly EDSM problems that were introduced very recently by Gabory et al. (Information and Computation, 2025).

Cite as

Solon P. Pissis, Jakub Radoszewski, and Wiktor Zuba. Faster Approximate Elastic-Degenerate String Matching - Part A. In 36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 331, pp. 28:1-28:19, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{pissis_et_al:LIPIcs.CPM.2025.28,
  author =	{Pissis, Solon P. and Radoszewski, Jakub and Zuba, Wiktor},
  title =	{{Faster Approximate Elastic-Degenerate String Matching - Part A}},
  booktitle =	{36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025)},
  pages =	{28:1--28:19},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-369-0},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{331},
  editor =	{Bonizzoni, Paola and M\"{a}kinen, Veli},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2025.28},
  URN =		{urn:nbn:de:0030-drops-231227},
  doi =		{10.4230/LIPIcs.CPM.2025.28},
  annote =	{Keywords: ED string, approximate string matching, Hamming distance, edit distance}
}
Document
Shortest Undirected Paths in de Bruijn Graphs

Authors: Wiktor Zuba, Oded Lachish, and Solon P. Pissis

Published in: LIPIcs, Volume 331, 36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025)


Abstract
Computing shortest directed paths in de Bruijn graphs is well studied and well understood. This is not the case for computing undirected paths, which is much more challenging algorithmically. In this paper, we present a general framework for computing shortest undirected paths in arbitrary de Bruijn graphs, that is, arbitrary subgraphs of the complete de Bruijn graph. We then present an application of our techniques for making any arbitrary order-k de Bruijn graph G(V,E) weakly connected by adding a set of edges of minimum total cost. This improves the running time of the recent (2-2/d)-approximation algorithm by Bernardini et al. [CPM 2024] from 𝒪(k|V|²) to 𝒪(k|V|log d) time, where d is the number of weakly connected components of graph G.

Cite as

Wiktor Zuba, Oded Lachish, and Solon P. Pissis. Shortest Undirected Paths in de Bruijn Graphs. In 36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025). Leibniz International Proceedings in Informatics (LIPIcs), Volume 331, pp. 12:1-12:13, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2025)


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@InProceedings{zuba_et_al:LIPIcs.CPM.2025.12,
  author =	{Zuba, Wiktor and Lachish, Oded and Pissis, Solon P.},
  title =	{{Shortest Undirected Paths in de Bruijn Graphs}},
  booktitle =	{36th Annual Symposium on Combinatorial Pattern Matching (CPM 2025)},
  pages =	{12:1--12:13},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-369-0},
  ISSN =	{1868-8969},
  year =	{2025},
  volume =	{331},
  editor =	{Bonizzoni, Paola and M\"{a}kinen, Veli},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2025.12},
  URN =		{urn:nbn:de:0030-drops-231060},
  doi =		{10.4230/LIPIcs.CPM.2025.12},
  annote =	{Keywords: string algorithm, graph algorithm, de Bruijn graph, Eulerian graph}
}
Document
Approximate Suffix-Prefix Dictionary Queries

Authors: Wiktor Zuba, Grigorios Loukides, Solon P. Pissis, and Sharma V. Thankachan

Published in: LIPIcs, Volume 306, 49th International Symposium on Mathematical Foundations of Computer Science (MFCS 2024)


Abstract
In the all-pairs suffix-prefix (APSP) problem [Gusfield et al., Inf. Process. Lett. 1992], we are given a dictionary R of r strings, S₁,…,S_r, of total length n, and we are asked to find the length SPL_{i,j} of the longest string that is both a suffix of S_i and a prefix of S_j, for all i,j ∈ [1..r]. APSP is a classic problem in string algorithms with applications in bioinformatics, especially in sequence assembly. Since r = |R| is typically very large in real-world applications, considering all r² pairs of strings explicitly is prohibitive. This is when the data structure variant of APSP makes sense; in the same spirit as distance oracles computing shortest paths between any two vertices given online. We show how to quickly locate k-approximate matches (under the Hamming or the edit distance) in R using a version of the k-errata tree [Cole et al., STOC 2004] that we introduce. Let SPL^k_{i,j} be the length of the longest suffix of S_i that is at distance at most k from a prefix of S_j. In particular, for any k = 𝒪(1), we show an 𝒪(nlog^k n)-sized data structure to support the following queries: - One-to-One^k(i,j): output SPL^k_{i,j} in 𝒪(log^k nlog log n) time. - Report^k(i,d): output all j ∈ [1..r], such that SPL^k_{i,j} ≥ d, in 𝒪(log^{k}n(log n/log log n+output)) time, where output denotes the size of the output. In fact, our algorithms work for any value of k not just for k = 𝒪(1), but the formulas bounding the complexities get much more complicated for larger values of k.

Cite as

Wiktor Zuba, Grigorios Loukides, Solon P. Pissis, and Sharma V. Thankachan. Approximate Suffix-Prefix Dictionary Queries. In 49th International Symposium on Mathematical Foundations of Computer Science (MFCS 2024). Leibniz International Proceedings in Informatics (LIPIcs), Volume 306, pp. 85:1-85:18, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2024)


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@InProceedings{zuba_et_al:LIPIcs.MFCS.2024.85,
  author =	{Zuba, Wiktor and Loukides, Grigorios and Pissis, Solon P. and Thankachan, Sharma V.},
  title =	{{Approximate Suffix-Prefix Dictionary Queries}},
  booktitle =	{49th International Symposium on Mathematical Foundations of Computer Science (MFCS 2024)},
  pages =	{85:1--85:18},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-335-5},
  ISSN =	{1868-8969},
  year =	{2024},
  volume =	{306},
  editor =	{Kr\'{a}lovi\v{c}, Rastislav and Ku\v{c}era, Anton{\'\i}n},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.MFCS.2024.85},
  URN =		{urn:nbn:de:0030-drops-206416},
  doi =		{10.4230/LIPIcs.MFCS.2024.85},
  annote =	{Keywords: all-pairs suffix-prefix, suffix-prefix queries, suffix tree, k-errata tree}
}
Document
Connecting de Bruijn Graphs

Authors: Giulia Bernardini, Huiping Chen, Inge Li Gørtz, Christoffer Krogh, Grigorios Loukides, Solon P. Pissis, Leen Stougie, and Michelle Sweering

Published in: LIPIcs, Volume 296, 35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024)


Abstract
We study the problem of making a de Bruijn graph (dBG), constructed from a collection of strings, weakly connected while minimizing the total cost of edge additions. The input graph is a dBG that can be made weakly connected by adding edges (along with extra nodes if needed) from the underlying complete dBG. The problem arises from genome reconstruction, where the dBG is constructed from a set of sequences generated from a genome sample by a sequencing experiment. Due to sequencing errors, the dBG is never Eulerian in practice and is often not even weakly connected. We show the following results for a dBG G(V,E) of order k consisting of d weakly connected components: 1) Making G weakly connected by adding a set of edges of minimal total cost is NP-hard. 2) No PTAS exists for making G weakly connected by adding a set of edges of minimal total cost (unless the unique games conjecture fails). We complement this result by showing that there does exist a polynomial-time (2-2/d)-approximation algorithm for the problem. 3) We consider a restricted version of the above problem, where we are asked to make G weakly connected by only adding directed paths between pairs of components. We show that making G weakly connected by adding d-1 such paths of minimal total cost can be done in 𝒪(k|V|α(|V|)+|E|) time, where α(⋅) is the inverse Ackermann function. This improves on the 𝒪(k|V|log(|V|)+|E|)-time algorithm proposed by Bernardini et al. [CPM 2022] for the same restricted problem. 4) An ILP formulation of polynomial size for making G Eulerian with minimal total cost.

Cite as

Giulia Bernardini, Huiping Chen, Inge Li Gørtz, Christoffer Krogh, Grigorios Loukides, Solon P. Pissis, Leen Stougie, and Michelle Sweering. Connecting de Bruijn Graphs. In 35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024). Leibniz International Proceedings in Informatics (LIPIcs), Volume 296, pp. 6:1-6:16, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2024)


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@InProceedings{bernardini_et_al:LIPIcs.CPM.2024.6,
  author =	{Bernardini, Giulia and Chen, Huiping and G{\o}rtz, Inge Li and Krogh, Christoffer and Loukides, Grigorios and Pissis, Solon P. and Stougie, Leen and Sweering, Michelle},
  title =	{{Connecting de Bruijn Graphs}},
  booktitle =	{35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024)},
  pages =	{6:1--6:16},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-326-3},
  ISSN =	{1868-8969},
  year =	{2024},
  volume =	{296},
  editor =	{Inenaga, Shunsuke and Puglisi, Simon J.},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2024.6},
  URN =		{urn:nbn:de:0030-drops-201168},
  doi =		{10.4230/LIPIcs.CPM.2024.6},
  annote =	{Keywords: string algorithm, graph algorithm, de Bruijn graph, Eulerian graph}
}
Document
Minimizing the Minimizers via Alphabet Reordering

Authors: Hilde Verbeek, Lorraine A.K. Ayad, Grigorios Loukides, and Solon P. Pissis

Published in: LIPIcs, Volume 296, 35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024)


Abstract
Minimizers sampling is one of the most widely-used mechanisms for sampling strings [Roberts et al., Bioinformatics 2004]. Let S = S[1]… S[n] be a string over a totally ordered alphabet Σ. Further let w ≥ 2 and k ≥ 1 be two integers. The minimizer of S[i..i+w+k-2] is the smallest position in [i,i+w-1] where the lexicographically smallest length-k substring of S[i..i+w+k-2] starts. The set of minimizers over all i ∈ [1,n-w-k+2] is the set ℳ_{w,k}(S) of the minimizers of S. We consider the following basic problem: Given S, w, and k, can we efficiently compute a total order on Σ that minimizes |ℳ_{w,k}(S)|? We show that this is unlikely by proving that the problem is NP-hard for any w ≥ 3 and k ≥ 1. Our result provides theoretical justification as to why there exist no exact algorithms for minimizing the minimizers samples, while there exists a plethora of heuristics for the same purpose.

Cite as

Hilde Verbeek, Lorraine A.K. Ayad, Grigorios Loukides, and Solon P. Pissis. Minimizing the Minimizers via Alphabet Reordering. In 35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024). Leibniz International Proceedings in Informatics (LIPIcs), Volume 296, pp. 28:1-28:13, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2024)


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@InProceedings{verbeek_et_al:LIPIcs.CPM.2024.28,
  author =	{Verbeek, Hilde and Ayad, Lorraine A.K. and Loukides, Grigorios and Pissis, Solon P.},
  title =	{{Minimizing the Minimizers via Alphabet Reordering}},
  booktitle =	{35th Annual Symposium on Combinatorial Pattern Matching (CPM 2024)},
  pages =	{28:1--28:13},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-326-3},
  ISSN =	{1868-8969},
  year =	{2024},
  volume =	{296},
  editor =	{Inenaga, Shunsuke and Puglisi, Simon J.},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2024.28},
  URN =		{urn:nbn:de:0030-drops-201383},
  doi =		{10.4230/LIPIcs.CPM.2024.28},
  annote =	{Keywords: sequence analysis, minimizers, alphabet reordering, feedback arc set}
}
Document
Suffix-Prefix Queries on a Dictionary

Authors: Grigorios Loukides, Solon P. Pissis, Sharma V. Thankachan, and Wiktor Zuba

Published in: LIPIcs, Volume 259, 34th Annual Symposium on Combinatorial Pattern Matching (CPM 2023)


Abstract
In the all-pairs suffix-prefix (APSP) problem, we are given a dictionary R of k strings, S_1,…,S_k, of total length n, and we are asked to find the length SPL_{i,j} of the longest string that is both a suffix of S_i and a prefix of S_j, for all i,j ∈ [1,k]. APSP is a classic problem in string algorithms with many applications in bioinformatics. When all strings of the dictionary are over an integer alphabet of size σ ≤ n^𝒪(1), APSP can be solved in the optimal 𝒪(n+k²) time with the use of the generalized suffix tree of the dictionary [Gusfield et al., Inf. Process. Lett. 1992]. In many bioinformatics applications, such as in sequence assembly, the size k of dictionary R is very large. In particular, k² usually dominates n, and thus the k² factor is the bottleneck both in the time and in the space complexity of such applications. We thus initiate a holistic study on several data structure variants of APSP. In particular, we consider the following types of queries: - One-to-One(i,j): output SPL_{i,j}. - One-to-All(i): output SPL_{i,j} for every j ∈ [1,k]. - Report(i,𝓁): output all distinct j ∈ [1,k] such that SPL_{i,j} ≥ 𝓁, where 𝓁 ≥ 0 is an integer. - Count(i,𝓁): output the number of distinct j ∈ [1,k] such that SPL_{i,j} ≥ 𝓁, where 𝓁 ≥ 0 is an integer. - Top(i,K): output K distinct j ∈ [1,k] with the highest values of SPL_{i,j} breaking ties arbitrarily. We assume the standard word RAM model of computation with word size w = Ω(log n) and an integer alphabet of size σ ≤ n^𝒪(1). We show the following upper bounds: Query | Space (words) | Query time | Note One-to-One(i,j) | 𝒪(n) | 𝒪(log log k) | Theorem 11 One-to-All(i) | 𝒪(n) | 𝒪(k) | Theorem 14 Report(i,𝓁) | 𝒪(n) | 𝒪(log n/log log n+output) | Theorem 19(i) Count(i,𝓁) | 𝒪(n) | 𝒪(log n/log log n) | Theorem 19(ii) Top(i,K) | 𝒪(n) | 𝒪(log² n/log log n+K) | Theorem 22 We also present efficient algorithms for constructing these data structures.

Cite as

Grigorios Loukides, Solon P. Pissis, Sharma V. Thankachan, and Wiktor Zuba. Suffix-Prefix Queries on a Dictionary. In 34th Annual Symposium on Combinatorial Pattern Matching (CPM 2023). Leibniz International Proceedings in Informatics (LIPIcs), Volume 259, pp. 21:1-21:20, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2023)


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@InProceedings{loukides_et_al:LIPIcs.CPM.2023.21,
  author =	{Loukides, Grigorios and Pissis, Solon P. and Thankachan, Sharma V. and Zuba, Wiktor},
  title =	{{Suffix-Prefix Queries on a Dictionary}},
  booktitle =	{34th Annual Symposium on Combinatorial Pattern Matching (CPM 2023)},
  pages =	{21:1--21:20},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-276-1},
  ISSN =	{1868-8969},
  year =	{2023},
  volume =	{259},
  editor =	{Bulteau, Laurent and Lipt\'{a}k, Zsuzsanna},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2023.21},
  URN =		{urn:nbn:de:0030-drops-179757},
  doi =		{10.4230/LIPIcs.CPM.2023.21},
  annote =	{Keywords: all-pairs suffix-prefix, suffix-prefix queries, internal pattern matching}
}
Document
Making de Bruijn Graphs Eulerian

Authors: Giulia Bernardini, Huiping Chen, Grigorios Loukides, Solon P. Pissis, Leen Stougie, and Michelle Sweering

Published in: LIPIcs, Volume 223, 33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022)


Abstract
A directed multigraph is called Eulerian if it has a circuit which uses each edge exactly once. Euler’s theorem tells us that a weakly connected directed multigraph is Eulerian if and only if every node is balanced. Given a collection S of strings over an alphabet Σ, the de Bruijn graph (dBG) of order k of S is a directed multigraph G_{S,k}(V,E), where V is the set of length-(k-1) substrings of the strings in S, and G_{S,k} contains an edge (u,v) with multiplicity m_{u,v}, if and only if the string u[0]⋅ v is equal to the string u⋅ v[k-2] and this string occurs exactly m_{u,v} times in total in strings in S. Let G_{Σ,k}(V_{Σ,k},E_{Σ,k}) be the complete dBG of Σ^k. The Eulerian Extension (EE) problem on G_{S,k} asks to extend G_{S,k} with a set ℬ of nodes from V_{Σ,k} and a smallest multiset 𝒜 of edges from E_{Σ,k} to make it Eulerian. Note that extending dBGs is algorithmically much more challenging than extending general directed multigraphs because some edges in dBGs are by definition forbidden. Extending dBGs lies at the heart of sequence assembly [Medvedev et al., WABI 2007], one of the most important tasks in bioinformatics. The novelty of our work with respect to existing works is that we allow not only to duplicate existing edges of G_{S,k} but to also add novel edges and nodes, in an effort to (i) connect multiple components and (ii) reduce the total EE cost. It is easy to show that EE on G_{S,k} is NP-hard via a reduction from shortest common superstring. We further show that EE remains NP-hard, even when we are not allowed to add new nodes, via a highly non-trivial reduction from 3-SAT. We thus investigate the following two problems underlying EE in dBGs: 1) When G_{S,k} is not weakly connected, we are asked to connect its d > 1 components using a minimum-weight spanning tree, whose edges are paths on the underlying G_{Σ,k} and weights are the corresponding path lengths. This way of connecting guarantees that no new unbalanced node is added. We show that this problem can be solved in 𝒪(|V|klog d+|E|) time, which is nearly optimal, since the size of G_{S,k} is Θ(|V|k+|E|). 2) When G_{S,k} is not balanced, we are asked to extend G_{S,k} to H_{S,k}(V∪ℬ,E∪𝒜) such that every node of H_{S,k} is balanced and the total number |𝒜| of added edges is minimized. We show that this problem can be solved in the optimal 𝒪(k|V| + |E|+ |𝒜|) time. Let us stress that, although our main contributions are theoretical, the algorithms we design for the above two problems are practical. We combine the two algorithms in one method that makes any dBG Eulerian; and show experimentally that the cost of the obtained feasible solutions on real-world dBGs is substantially smaller than the corresponding cost obtained by existing greedy approaches.

Cite as

Giulia Bernardini, Huiping Chen, Grigorios Loukides, Solon P. Pissis, Leen Stougie, and Michelle Sweering. Making de Bruijn Graphs Eulerian. In 33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022). Leibniz International Proceedings in Informatics (LIPIcs), Volume 223, pp. 12:1-12:18, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2022)


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@InProceedings{bernardini_et_al:LIPIcs.CPM.2022.12,
  author =	{Bernardini, Giulia and Chen, Huiping and Loukides, Grigorios and Pissis, Solon P. and Stougie, Leen and Sweering, Michelle},
  title =	{{Making de Bruijn Graphs Eulerian}},
  booktitle =	{33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022)},
  pages =	{12:1--12:18},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-234-1},
  ISSN =	{1868-8969},
  year =	{2022},
  volume =	{223},
  editor =	{Bannai, Hideo and Holub, Jan},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2022.12},
  URN =		{urn:nbn:de:0030-drops-161391},
  doi =		{10.4230/LIPIcs.CPM.2022.12},
  annote =	{Keywords: string algorithms, graph algorithms, Eulerian graph, de Bruijn graph}
}
Document
On Strings Having the Same Length- k Substrings

Authors: Giulia Bernardini, Alessio Conte, Esteban Gabory, Roberto Grossi, Grigorios Loukides, Solon P. Pissis, Giulia Punzi, and Michelle Sweering

Published in: LIPIcs, Volume 223, 33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022)


Abstract
Let Substr_k(X) denote the set of length-k substrings of a given string X for a given integer k > 0. We study the following basic string problem, called z-Shortest 𝒮_k-Equivalent Strings: Given a set 𝒮_k of n length-k strings and an integer z > 0, list z shortest distinct strings T₁,…,T_z such that Substr_k(T_i) = 𝒮_k, for all i ∈ [1,z]. The z-Shortest 𝒮_k-Equivalent Strings problem arises naturally as an encoding problem in many real-world applications; e.g., in data privacy, in data compression, and in bioinformatics. The 1-Shortest 𝒮_k-Equivalent Strings, referred to as Shortest 𝒮_k-Equivalent String, asks for a shortest string X such that Substr_k(X) = 𝒮_k. Our main contributions are summarized below: - Given a directed graph G(V,E), the Directed Chinese Postman (DCP) problem asks for a shortest closed walk that visits every edge of G at least once. DCP can be solved in 𝒪̃(|E||V|) time using an algorithm for min-cost flow. We show, via a non-trivial reduction, that if Shortest 𝒮_k-Equivalent String over a binary alphabet has a near-linear-time solution then so does DCP. - We show that the length of a shortest string output by Shortest 𝒮_k-Equivalent String is in 𝒪(k+n²). We generalize this bound by showing that the total length of z shortest strings is in 𝒪(zk+zn²+z²n). We derive these upper bounds by showing (asymptotically tight) bounds on the total length of z shortest Eulerian walks in general directed graphs. - We present an algorithm for solving z-Shortest 𝒮_k-Equivalent Strings in 𝒪(nk+n²log²n+zn²log n+|output|) time. If z = 1, the time becomes 𝒪(nk+n²log²n) by the fact that the size of the input is Θ(nk) and the size of the output is 𝒪(k+n²).

Cite as

Giulia Bernardini, Alessio Conte, Esteban Gabory, Roberto Grossi, Grigorios Loukides, Solon P. Pissis, Giulia Punzi, and Michelle Sweering. On Strings Having the Same Length- k Substrings. In 33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022). Leibniz International Proceedings in Informatics (LIPIcs), Volume 223, pp. 16:1-16:17, Schloss Dagstuhl – Leibniz-Zentrum für Informatik (2022)


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@InProceedings{bernardini_et_al:LIPIcs.CPM.2022.16,
  author =	{Bernardini, Giulia and Conte, Alessio and Gabory, Esteban and Grossi, Roberto and Loukides, Grigorios and Pissis, Solon P. and Punzi, Giulia and Sweering, Michelle},
  title =	{{On Strings Having the Same Length- k Substrings}},
  booktitle =	{33rd Annual Symposium on Combinatorial Pattern Matching (CPM 2022)},
  pages =	{16:1--16:17},
  series =	{Leibniz International Proceedings in Informatics (LIPIcs)},
  ISBN =	{978-3-95977-234-1},
  ISSN =	{1868-8969},
  year =	{2022},
  volume =	{223},
  editor =	{Bannai, Hideo and Holub, Jan},
  publisher =	{Schloss Dagstuhl -- Leibniz-Zentrum f{\"u}r Informatik},
  address =	{Dagstuhl, Germany},
  URL =		{https://drops.dagstuhl.de/entities/document/10.4230/LIPIcs.CPM.2022.16},
  URN =		{urn:nbn:de:0030-drops-161439},
  doi =		{10.4230/LIPIcs.CPM.2022.16},
  annote =	{Keywords: string algorithms, combinatorics on words, de Bruijn graph, Chinese Postman}
}
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